Cardinals vs. Red Sox Prediction: Boston Predicted to Win Saturday's MLB Matchup [4/5/2025]

The Boston Red Sox will square off with the St. Louis Cardinals in MLB action at Fenway Park on Saturday, starting at 4:10PM ET.

Richard Fitts (0-1, 4.50 ERA) will start for the Red Sox, while the Cardinals are going with Andre Pallante (1-0, 3.60 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Red Sox as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's St. Louis-Boston game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Red Sox are more likely to win, while the Cardinals have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Cardinals vs. Red Sox predictions page.

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Cardinals vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB game between the Cardinals and Red Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Red Sox a 52% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 66% chance of covering the run line, while the 8.5-run over/under has a 54% chance of going over.

Pre-Game Probabilities

Last Updated: 7:28PM, Apr 5

Moneyline

Over / Under

Run Line

Cardinals

Win %

48%

52%

+118

-125

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Red Sox

Cardinals STL

+118

Win %

48%

52%

See Matchup

Red Sox BOS

-125

Andre Pallante 1-0, 3.60 ERA

Richard Fitts 0-1, 4.50 ERA

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Cardinals vs. Red Sox Odds [4/5/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Red Sox Picks and Best Bets

Our model's biggest edge in today's Cardinals vs. Red Sox matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Cardinals vs. Red Sox Game-Day Updates and Essential Details

Saturday's MLB game between the Red Sox and Cardinals at Fenway Park is scheduled to start at 4:10PM ET.

• Who: St. Louis Cardinals vs. Boston Red Sox
• Date: Saturday, April 5, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Fenway Park

Dimers.com's full preview of Saturday's Cardinals vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Boston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Red Sox, with a 52% win probability, will likely beat the Cardinals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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