Pirates vs. Reds Prediction: Cincinnati Predicted to Win Friday's MLB Matchup [4/11/2025]

The Cincinnati Reds and Pittsburgh Pirates will meet in MLB action at Great American Ball Park on Friday, starting at 6:40PM ET.

The Reds will have Brady Singer (2-0, 2.25 ERA) as their starting pitcher, up against Bailey Falter (0-1, 8.10 ERA) for the Pirates.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Pittsburgh-Cincinnati game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Reds' chance of winning is 59%, while the Pirates' is 41%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Pirates vs. Reds predictions page.

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Pirates vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's MLB game between the Pirates and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Reds a 59% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 60% chance of covering the run line, while the over/under total of 8 runs has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 11

Moneyline

Over / Under

Run Line

Pirates

Win %

41%

59%

+145

-165

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Reds

Pirates PIT

+145

Win %

41%

59%

See Matchup

Reds CIN

-165

Bailey Falter 0-1, 8.10 ERA

Brady Singer 2-0, 2.25 ERA

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Pirates vs. Reds Odds [4/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Pirates vs. Reds Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Reds matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

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Pirates vs. Reds Game-Day Updates and Essential Details

Friday's MLB game between the Reds and Pirates at Great American Ball Park is scheduled to start at 6:40PM ET.

• Who: Pittsburgh Pirates vs. Cincinnati Reds
• Date: Friday, April 11, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Great American Ball Park

Dimers.com's full preview of Friday's Pirates vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 59% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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