Royals vs. Guardians Prediction: Cleveland Predicted to Win Friday's MLB Matchup [4/11/2025]

MLB action continues on Friday at 6:10PM ET as the Kansas City Royals square off with the Cleveland Guardians at Progressive Field.

The Guardians will send Tanner Bibee (1-1, 6.52 ERA) to the mound, up against Kris Bubic (2-0, 0.00 ERA) for the Royals.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Guardians as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Kansas City-Cleveland game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Guardians' chance of winning is 55%, while the Royals' is 45%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Royals vs. Guardians predictions page.

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Royals vs. Royals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Friday's MLB game between the Royals and Guardians 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Guardians a 55% chance of beating the Royals.

According to our model, the Royals (+1.5) have a 64% chance of covering the run line, while the over/under total of 6.5 runs has a 57% chance of going over.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 11

Moneyline

Over / Under

Run Line

Royals

Win %

46%

54%

+110

-125

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Guardians

Royals KC

+110

Win %

46%

54%

See Matchup

Guardians CLE

-125

Kris Bubic 2-0, 0.00 ERA

Tanner Bibee 1-1, 6.52 ERA

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Royals vs. Guardians Odds [4/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Royals vs. Guardians Picks and Best Bets

Our model's biggest edge in today's Royals vs. Guardians matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Royals vs. Guardians Game-Day Updates and Essential Details

Friday's MLB action between the Guardians and Royals at Progressive Field is scheduled to start at 6:10PM ET.

• Who: Kansas City Royals vs. Cleveland Guardians
• Date: Friday, April 11, 2025
• Time: 6:10PM ET/3:10PM PT
• Venue: Progressive Field

Dimers.com's comprehensive preview of Friday's Royals vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Kansas City vs. Cleveland picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Guardians, with a 55% win probability, will likely beat the Royals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Royals vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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