Southampton vs. Crystal Palace Prediction, Odds, Premier League Picks [4/2/2025]

Southampton will square off with Crystal Palace in Premier League action at St. Mary's Stadium on Wednesday, beginning at 2:45PM ET.

Based on the latest simulations, Dimers' proven Premier League model (see Dimers Pro for full access) predicts Crystal Palace as the most likely winner of the game.

"Our team has simulated the outcome of Wednesday's Southampton-Crystal Palace game 10,000 times," said Jason Bevilacqua from Dimers.

"After incorporating the most recent updates and numerous additional inputs, our prediction gives Southampton a 20.9% chance of winning, Crystal Palace a 56.3% chance, and a 22.7% chance of a draw."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Southampton vs. Crystal Palace predictions page.

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Southampton vs. Crystal Palace Prediction: Who Will Win?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's Premier League match between Southampton and Crystal Palace 10,000 times as part of our Premier League predictions coverage.

Our famous predictive model indicates a 20.9% chance of Southampton winning, a 56.3% chance for Crystal Palace, and a 22.7% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 55% chance of going over, according to our model.

Southampton vs. Crystal Palace Odds

We have sourced the best Premier League odds in America for this game, which are listed here:

Moneyline

Southampton	Crystal Palace	Draw
+500	-175	+320

Total Goals

Over 2.5	Under 2.5
-143	+107

All odds are correct at the time of publication and are subject to change.

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Southampton vs. Crystal Palace Picks and Best Bets

Our model's strongest edge in the Southampton vs. Crystal Palace matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best Premier League picks and Premier League best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Southampton vs. Crystal Palace: Correct Score and BTTS Predictions

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

Final Score	Probability
SOU 1-1 CRY	10.8%
SOU 0-1 CRY	10.5%
SOU 1-2 CRY	9.9%

When it comes to the both teams to score (BTTS) market, we project a 54.0% chance that both teams scoring, and a 46.0% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score may differ from our predicted winner.

Southampton vs. Crystal Palace Game-Day Updates and Essential Details

Wednesday's Premier League action between Southampton and Crystal Palace at St. Mary's Stadium is scheduled to commence in the United States at 2:45PM ET.

• Who: Southampton vs. Crystal Palace
• Date: Wednesday, April 2, 2025
• Time: 2:45PM ET/11:45AM PT
• Venue: St. Mary's Stadium

Dimers.com's full preview of Wednesday's Southampton vs. Crystal Palace matchup includes our prediction, picks and the latest betting odds.

Before making any Crystal Palace vs. Southampton picks, be sure to check out the latest Premier League predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Southampton has a 20.9% win probability on Wednesday, Crystal Palace has a 56.3% win probability, and there is a 22.7% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Southampton vs. Crystal Palace insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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