NFL Odds and Games Week 2: Spreads, Moneylines, Totals [2024]

Week 2 of the NFL season is here, bringing the latest spreads, moneylines and totals for every matchup.

As we head into Week 2 of the NFL season, the slate is stacked with games that promise excitement and plenty of betting opportunities.

The action begins with a Thursday night clash between the Buffalo Bills and Miami Dolphins. The Dolphins enter as 2.5-point favorites, setting the stage for a tightly contested matchup.

Below, you'll find detailed Vegas odds and key information for each game, ensuring you have the best NFL odds at your fingertips to confidently place your NFL best bets.

NFL Week 2	Spread	Moneyline	Total
Bills vs. Dolphins	+2.5 (-105) -2.5 (-110)	+120 -135	o48.5 (-112) u48.5 (-105)
Saints vs. Cowboys	+6.5 (-110) -6.5 (-104)	+230 -270	o47 (-108) u47 (-112)
Raiders vs. Ravens	-+8.5 (-110) -8.5 (-110)	+370 -425	o41.5 (-110) u41.5 (-110)
Giants vs. Commanders	+1.5 (-108) -1.5 (-105)	+105 -116	o43 (-110) u43 (-110)
Chargers vs. Panthers	-6 (-110) +6 (-110)	-245 +220	o39 (-108) u39 (-112)
Colts vs. Packers	-3 (-102) +3 (-110)	-148 +135	o40.5 (-112) u40.5 (-108)
49ers vs. Vikings	-6.5 (-102) +6.5 (-120)	-238 +215	o45.5 (-110) u45.5 (-105)
Browns vs. Jaguars	+3 (-110) -3 (-105)	+138 -148	o42.5 (-110) u42.5 (-120)
Seahawks vs. Patriots	-3.5 (-105) +3.5 (-105)	-180 +176	o38.5 (-110) u38.5 (-110)
Buccaneers vs. Lions	+7.5 (-110) -7.5 (-108)	+295 -360	o51.5 (-105) u51.5 (-110)
Rams vs. Cardinals	+1.5 (-115) -1.5 (-105)	+102 -118	o48.5 (-112) u48.5 (-108)
Steelers vs. Broncos	-2.5 (-110) +2.5 (-108)	-140 +124	o36.5 (-110) u36.5 (-105)
Bengals vs. Chiefs	+5.5 (-110) -5.5 (-110)	+200 -218	o47.5 (-110) u47.5 (-110)
Bears vs. Texans	+6.5 (-110) -6.5 (-102)	+225 -258	o45.5 (-108) u45.5 (-105)
Falcons vs. Eagles	+6.5 (-106) -6.5 (-112)	+260 -300	o47 (-110) u47 (-108)

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NFL Odds for Every Game of NFL Week 2

Bills vs. Dolphins Odds

• Matchup: Buffalo Bills vs. Miami Dolphins
• Spread: Bills +2.5 (-105), Dolphins -2.5 (-110)
• Total: Over/Under 48.5 (-112/-105)
• Moneyline: Bills +120, Dolphins -135
• Dimers' Win Probabilities: Bills 41%, Dolphins 59%
• Date: Thursday, September 12, 2024
• Time: 8:15pm
• Venue: Hard Rock Stadium

In a game likely to be closely contested, the Dolphins are 2.5-point favorites on Thursday Night Football against the Bills. The total line is set at 48.5 points, which is considered high for the over/under.

The NFL Week 2 game between the Bills and Dolphins at Hard Rock Stadium is scheduled for 8:15pm on Thursday. For detailed analysis, see our full Bills vs Dolphins prediction.

Saints vs. Cowboys Odds

• Matchup: New Orleans Saints vs. Dallas Cowboys
• Spread: Saints +6.5 (-110), Cowboys -6.5 (-104)
• Total: Over/Under 47 (-108/-112)
• Moneyline: Saints +230, Cowboys -270
• Dimers' Win Probabilities: Saints 30%, Cowboys 70%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: AT&T Stadium

By roughly a touchdown, the Cowboys face a -6.5 point spread as favorites in their clash against the Saints. The total line is set at 47 points, which is considered high for the over/under.

The game between the Saints and Cowboys at AT&T Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Saints vs Cowboys prediction.

Raiders vs. Ravens Odds

• Matchup: Las Vegas Raiders vs. Baltimore Ravens
• Spread: Raiders +8.5 (-110), Ravens -8.5 (-110)
• Total: Over/Under 41.5 (-110/-110)
• Moneyline: Raiders +370, Ravens -425
• Dimers' Win Probabilities: Raiders 21%, Ravens 79%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: M&T Bank Stadium

Holding a solid advantage, the Ravens are 8.5-point favorites at the spread in their clash against the Raiders. The total line is set at 41.5 points.

This week's game between the Raiders and Ravens at M&T Bank Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Raiders vs Ravens prediction.

Giants vs. Commanders Odds

• Matchup: New York Giants vs. Washington Commanders
• Spread: Giants +1.5 (-108), Commanders -1.5 (-105)
• Total: Over/Under 43 (-110/-110)
• Moneyline: Giants +105, Commanders -116
• Dimers' Win Probabilities: Giants 41%, Commanders 59%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Northwest Stadium

In a game likely to be closely contested, the Commanders are 1.5-point favorites in their clash against the Giants. The total line is set at 43 points.

The NFL Week 2 matchup between the Giants and Commanders at Northwest Stadium is scheduled for 1:00pm on Sunday. For Dimers' full betting preview, check out our Giants vs Commanders prediction.

Chargers vs. Panthers Odds

• Matchup: Los Angeles Chargers vs. Carolina Panthers
• Spread: Chargers -6 (-110), Panthers +6 (-110)
• Total: Over/Under 39 (-108/-112)
• Moneyline: Chargers -245, Panthers +220
• Dimers' Win Probabilities: Chargers 72%, Panthers 28%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Bank of America Stadium

By roughly a touchdown, the Panthers face a +6 point spread as underdogs in their clash against the Chargers. The total line is set at 39 points, which is considered low for the over/under.

The clash between the Chargers and Panthers at Bank of America Stadium is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full Chargers vs Panthers prediction.

Colts vs. Packers Odds

• Matchup: Indianapolis Colts vs. Green Bay Packers
• Spread: Colts -3 (-102), Packers +3 (-110)
• Total: Over/Under 40.5 (-112/-108)
• Moneyline: Colts -148, Packers +135
• Dimers' Win Probabilities: Colts 59%, Packers 41%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Lambeau Field

In a game likely to be closely contested, the Packers are 3-point underdogs in their clash against the Colts. The total line is set at 40.5 points.

This week's clash between the Colts and Packers at Lambeau Field begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Colts vs Packers prediction.

49ers vs. Vikings Odds

• Matchup: San Francisco 49ers vs. Minnesota Vikings
• Spread: 49ers -6.5 (-102), Vikings +6.5 (-120)
• Total: Over/Under 45.5 (-110/-105)
• Moneyline: 49ers -238, Vikings +215
• Dimers' Win Probabilities: 49ers 66%, Vikings 34%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: U.S. Bank Stadium

By roughly a touchdown, the Vikings face a +6.5 point spread as underdogs in their clash against the 49ers. The total line is set at 45.5 points, which is considered high for the over/under.

The NFL Week 2 game between the 49ers and Vikings at U.S. Bank Stadium is scheduled for 1:00pm on Sunday. For more detailed analysis, check out our full 49ers vs Vikings prediction.

Browns vs. Jaguars Odds

• Matchup: Cleveland Browns vs. Jacksonville Jaguars
• Spread: Browns +3 (-110), Jaguars -3 (-105)
• Total: Over/Under 42.5 (-110/-120)
• Moneyline: Browns +138, Jaguars -148
• Dimers' Win Probabilities: Browns 40%, Jaguars 60%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: EverBank Stadium

In a game likely to be closely contested, the Jaguars are 3-point favorites in their clash against the Browns. The total line is set at 42.5 points.

The action between the Browns and Jaguars at EverBank Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Browns vs Jaguars prediction.

Seahawks vs. Patriots Odds

• Matchup: Seattle Seahawks vs. New England Patriots
• Spread: Seahawks -3.5 (-105), Patriots +3.5 (-105)
• Total: Over/Under 38.5 (-110/-110)
• Moneyline: Seahawks -180, Patriots +176
• Dimers' Win Probabilities: Seahawks 66%, Patriots 34%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Gillette Stadium

In a game likely to be closely contested, the Patriots are 3.5-point underdogs in their clash against the Seahawks. The total line is set at 38.5 points, which is considered low for the over/under.

This week's game between the Seahawks and Patriots at Gillette Stadium kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Seahawks vs Patriots prediction.

Jets vs. Titans Odds

• Matchup: New York Jets vs. Tennessee Titans
• Spread: Jets -3.5 (-108), Titans +3.5 (-110)
• Total: Over/Under 40.5 (-110/-105)
• Moneyline: Jets -170, Titans +155
• Dimers' Win Probabilities: Jets 63%, Titans 37%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Nissan Stadium

In what is expected to be a close game, the Titans are 3.5-point underdogs in their clash against the Jets. The total line is set at 40.5 points.

The NFL Week 2 action between the Jets and Titans at Nissan Stadium begins at 1:00pm on Sunday. For Dimers' full betting preview, check out our Jets vs Titans prediction.

Buccaneers vs. Lions Odds

• Matchup: Tampa Bay Buccaneers vs. Detroit Lions
• Spread: Buccaneers +7.5 (-110), Lions -7.5 (-108)
• Total: Over/Under 51.5 (-105/-110)
• Moneyline: Buccaneers +295, Lions -360
• Dimers' Win Probabilities: Buccaneers 27%, Lions 73%
• Date: Sunday, September 15, 2024
• Time: 1:00pm ET
• Venue: Ford Field

By roughly a touchdown, the Lions face a -7.5 point spread as favorites in their clash against the Buccaneers. Withan offensive shootout anticipated, the total line is set at 51.5 points.

The action between the Buccaneers and Lions at Ford Field kicks off at 1:00pm on Sunday. For more detailed analysis, check out our full Buccaneers vs Lions prediction.

Rams vs. Cardinals Odds

• Matchup: Los Angeles Rams vs. Arizona Cardinals
• Spread: Rams +1.5 (-115), Cardinals -1.5 (-105)
• Total: Over/Under 48.5 (-112/-108)
• Moneyline: Rams +102, Cardinals -118
• Dimers' Win Probabilities: Rams 48%, Cardinals 52%
• Date: Sunday, September 15, 2024
• Time: 4:05pm ET
• Venue: State Farm Stadium

In what appears to be a tight matchup, the Cardinals are 1.5-point favorites in their clash against the Rams. The total line is set at 48.5 points, which is considered high for the over/under.

This week's action between the Rams and Cardinals at State Farm Stadium kicks off at 4:05pm on Sunday. For Dimers' full betting preview, check out our Rams vs Cardinals prediction.

Steelers vs. Broncos Odds

• Matchup: Pittsburgh Steelers vs. Denver Broncos
• Spread: Steelers -2.5 (-110), Broncos +2.5 (-108)
• Total: Over/Under 36.5 (-110/-105)
• Moneyline: Steelers -140, Broncos +124
• Dimers' Win Probabilities: Steelers 60%, Broncos 40%
• Date: Sunday, September 15, 2024
• Time: 4:25pm ET
• Venue: Empower Field at Mile High

In what is expected to be a close game, the Broncos are 2.5-point underdogs in their clash against the Steelers. The total line is set at 36.5 points, which is considered low for the over/under.

The NFL Week 2 clash between the Steelers and Broncos at Empower Field at Mile High is scheduled for 4:25pm on Sunday. For more detailed analysis, check out our full Steelers vs Broncos prediction.

Bengals vs. Chiefs Odds

• Matchup: Cincinnati Bengals vs. Kansas City Chiefs
• Spread: Bengals +5.5 (-110), Chiefs -5.5 (-110)
• Total: Over/Under 47.5 (-110/-110)
• Moneyline: Bengals +200, Chiefs -218
• Dimers' Win Probabilities: Bengals 32%, Chiefs 68%
• Date: Sunday, September 15, 2024
• Time: 4:25pm ET
• Venue: GEHA Field at Arrowhead Stadium

By around a touchdown, the Chiefs face a -5.5 point spread as favorites in their clash against the Bengals. The total line is set at 47.5 points, which is considered high for the over/under.

The game between the Bengals and Chiefs at GEHA Field at Arrowhead Stadium is scheduled for 4:25pm on Sunday. For Dimers' full betting preview, check out our Bengals vs Chiefs prediction.

Bears vs. Texans Odds

• Matchup: Chicago Bears vs. Houston Texans
• Spread: Bears +6.5 (-110), Texans -6.5 (-102)
• Total: Over/Under 45.5 (-108/-105)
• Moneyline: Bears +225, Texans -258
• Dimers' Win Probabilities: Bears 29%, Texans 71%
• Date: Sunday, September 15, 2024
• Time: 8:20pm ET
• Venue: NRG Stadium

By roughly a touchdown, the Texans face a -6.5 point spread as favorites on Sunday Night Football against the Steelers. The total line is set at 45.5 points, which is considered high for the over/under.

This week's matchup between the Bears and Texans at NRG Stadium is scheduled for 8:20pm on Sunday. For more detailed analysis, check out our full Bears vs Texans prediction.

Falcons vs. Eagles Odds

• Matchup: Atlanta Falcons vs. Philadelphia Eagles
• Spread: Falcons +6.5 (-106), Eagles -6.5 (-112)
• Total: Over/Under 47 (-110/-108)
• Moneyline: Falcons +260, Eagles -300
• Dimers' Win Probabilities: Falcons 28%, Eagles 72%
• Date: Monday, September 16, 2024
• Time: 8:15pm ET
• Venue: Lincoln Financial Field

By around a touchdown, the Eagles face a -6.5 point spread as favorites on Monday Night Football against the Falcons. The total line is set at 47 points, which is considered high for the over/under.

The NFL Week 2 game between the Falcons and Eagles at Lincoln Financial Field is scheduled for 8:15pm on Monday. For Dimers' full betting preview, check out our Falcons vs Eagles prediction.

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NFL Odds: Week 2

Explore the odds for every NFL Week 2 matchup. Please note that these odds are accurate at the time of publication and may change.

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Conclusion

As Week 2 approaches, these NFL odds ensure you're ready for every game, right up to the matchup between the Falcons and Eagles on Monday Night Football, where the Eagles are favored by 6.5 points.

For more Week 2 betting coverage, view our NFL picks, NFL prop bets, NFL trends and NFL futures.