Orioles vs. Royals Prediction: Kansas City Predicted to Win Friday's MLB Matchup [4/4/2025]

The Kansas City Royals and Baltimore Orioles will meet in MLB action at Kauffman Stadium on Friday, starting at 7:40PM ET.

Seth Lugo (0-0, 5.40 ERA) will be the starting pitcher for the Royals, up against Dean Kremer (1-0, 8.44 ERA) for the Orioles.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Royals as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Baltimore-Kansas City game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Royals' chance of winning is 52%, while the Orioles' is 48%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Orioles vs. Royals predictions page.

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Orioles vs. Orioles Prediction: Who Will Win?

Using powerful machine learning and data, we have simulated the outcome of Friday's MLB game between the Orioles and Royals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Royals a 52% chance of defeating the Orioles.

According to our model, the 7.5-run over/under has a 60% chance of going over.

Pre-Game Probabilities

Last Updated: 11:27PM, Apr 4

Moneyline

Over / Under

Orioles

Win %

48%

52%

-107

-105

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Royals

Orioles BAL

-107

Win %

48%

52%

See Matchup

Royals KC

-105

Dean Kremer 1-0, 8.44 ERA

Seth Lugo 0-0, 5.40 ERA

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Orioles vs. Royals Odds [4/4/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Royals Picks and Best Bets

Our model's biggest edge in today's Orioles vs. Royals matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Orioles vs. Royals Game-Day Updates and Essential Details

Friday's MLB matchup between the Royals and Orioles at Kauffman Stadium is scheduled to commence at 7:40PM ET.

• Who: Baltimore Orioles vs. Kansas City Royals
• Date: Friday, April 4, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Kauffman Stadium

Dimers.com's comprehensive preview of Friday's Orioles vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Kansas City picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Royals, with a 52% win probability, will likely beat the Orioles on Friday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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