Tigers vs. Brewers Prediction: Milwaukee Predicted to Win Wednesday's MLB Matchup [4/16/2025]

The Milwaukee Brewers will take on the Detroit Tigers in MLB action at American Family Field on Wednesday, starting at 1:10PM ET.

Jose Quintana (1-0, 0.00 ERA) will be the starting pitcher for the Brewers, while the Tigers will counter with Keider Montero (0-0, 0.00 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Brewers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Detroit-Milwaukee game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Brewers' chance of winning at 57%, with the Tigers at 43%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Tigers vs. Brewers predictions page.

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Tigers vs. Tigers Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's MLB matchup between the Tigers and Brewers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Brewers a 57% chance of beating the Tigers.

According to our model, the Tigers (+1.5) have a 62% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of staying under.

Pre-Game Probabilities

Last Updated: 5:28PM, Apr 16

Moneyline

Over / Under

Run Line

Tigers

Win %

44%

56%

+135

-148

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Brewers

Tigers DET

+135

Win %

44%

56%

See Matchup

Brewers MIL

-148

Keider Montero 0-0, 0.00 ERA

Jose Quintana 1-0, 0.00 ERA

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Tigers vs. Brewers Odds [4/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Tigers vs. Brewers Picks and Best Bets

Our model's strongest edge in today's Tigers vs. Brewers matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Tigers vs. Brewers Game-Day Updates and Essential Details

Wednesday's MLB action between the Brewers and Tigers at American Family Field is scheduled to commence at 1:10PM ET.

• Who: Detroit Tigers vs. Milwaukee Brewers
• Date: Wednesday, April 16, 2025
• Time: 1:10PM ET/10:10AM PT
• Venue: American Family Field

Dimers.com's in-depth preview of Wednesday's Tigers vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Detroit vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Brewers, with a 57% win probability, will likely beat the Tigers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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