Giants vs. Astros Prediction: Houston Predicted to Win Monday's MLB Matchup [3/31/2025]

MLB action continues on Monday at 8:10PM ET as the San Francisco Giants take on the Houston Astros at Daikin Park.

The Astros will start Ronel Blanco (0-0, 0.00 ERA), up against Jordan Hicks (0-0, 0.00 ERA) for the Giants.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's San Francisco-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Astros are likely to win, with a probability of 53%, compared to the Giants' 47%."

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Giants vs. Astros predictions page.

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Giants vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Monday's MLB matchup between the Giants and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Astros a 53% chance of defeating the Giants.

According to our model, the Giants (+1.5) have a 65% chance of covering the run line, while the over/under total of 7.5 runs has a 56% chance of going over.

Pre-Game Probabilities

Last Updated: 12:27AM, Apr 1

Moneyline

Over / Under

Run Line

Giants

Win %

47%

53%

+114

-125

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Astros

Giants SF

+114

Win %

47%

53%

See Matchup

Astros HOU

-125

Jordan Hicks 0-0, 0.00 ERA

Ronel Blanco 0-0, 0.00 ERA

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Giants vs. Astros Odds [3/31/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Giants vs. Astros Picks and Best Bets

Our model's strongest edge in today's Giants vs. Astros matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Giants vs. Astros Game-Day Updates and Essential Details

Monday's MLB action between the Astros and Giants at Daikin Park is scheduled to start at 8:10PM ET.

• Who: San Francisco Giants vs. Houston Astros
• Date: Monday, March 31, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Monday's Giants vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Astros, with a 53% win probability, will likely beat the Giants on Monday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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