Reds vs. Brewers Prediction: Milwaukee Predicted to Win Friday's MLB Matchup [4/4/2025]

The Milwaukee Brewers will face the Cincinnati Reds, in what is expected to be a tight MLB game, at American Family Field on Friday, starting at 8:10PM ET.

The Brewers will have Tyler Alexander (0-0, 5.40 ERA) as their starting pitcher, up against Nick Martinez (0-1, 6.00 ERA) for the Reds.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Brewers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Cincinnati-Milwaukee game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Brewers' chance of winning is 51%, while the Reds' is 49%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Reds vs. Brewers predictions page.

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Reds vs. Reds Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Friday's MLB game between the Reds and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Brewers a 51% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 66% chance of covering the run line, while the over/under total of 8 runs has a 54% chance of going over.

Pre-Game Probabilities

Last Updated: 12:27AM, Apr 5

Moneyline

Over / Under

Run Line

Reds

Win %

49%

51%

+110

-124

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Brewers

Reds CIN

+110

Win %

49%

51%

See Matchup

Brewers MIL

-124

Nick Martinez 0-1, 6.00 ERA

Tyler Alexander 0-0, 5.40 ERA

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Reds vs. Brewers Odds [4/4/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Reds vs. Brewers Picks and Best Bets

Our model's strongest edge in today's Reds vs. Brewers matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Reds vs. Brewers Game-Day Updates and Essential Details

Friday's MLB matchup between the Brewers and Reds at American Family Field is scheduled to begin at 8:10PM ET.

• Who: Cincinnati Reds vs. Milwaukee Brewers
• Date: Friday, April 4, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: American Family Field

Dimers.com's comprehensive preview of Friday's Reds vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Cincinnati vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Brewers, with a 51% win probability, will likely beat the Reds on Friday.

AI and automation have enhanced this article to quickly deliver accurate Reds vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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