Yankees vs. Pirates Prediction: Yankees Predicted to Win Saturday's MLB Matchup [4/5/2025]

The Pittsburgh Pirates and New York Yankees will lock horns in MLB action at PNC Park on Saturday, starting at 4:05PM ET.

Bailey Falter (0-0, 3.00 ERA) will start for the Pirates, while the Yankees have opted for Marcus Stroman (0-0, 5.79 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Yankees as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's NY Yankees-Pittsburgh game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Yankees are more likely to win, while the Pirates have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Yankees vs. Pirates predictions page.

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Yankees vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB game between the Yankees and Pirates 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Yankees a 57% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 56% chance of covering the run line, while the 9.5-run over/under has a 55% chance of staying under.

Pre-Game Probabilities

Last Updated: 8:28PM, Apr 5

Moneyline

Over / Under

Run Line

Yankees

Win %

58%

42%

-140

+140

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Pirates

Yankees NYY

-140

Win %

58%

42%

See Matchup

Pirates PIT

+140

Marcus Stroman 0-0, 5.79 ERA

Bailey Falter 0-0, 3.00 ERA

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Yankees vs. Pirates Odds [4/5/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Yankees vs. Pirates Picks and Best Bets

Our model's biggest edge in today's Yankees vs. Pirates matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Yankees vs. Pirates Game-Day Updates and Essential Details

Saturday's MLB action between the Pirates and Yankees at PNC Park is scheduled to commence at 4:05PM ET.

• Who: New York Yankees vs. Pittsburgh Pirates
• Date: Saturday, April 5, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Saturday's Yankees vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any NY Yankees vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Yankees, with a 57% win probability, will likely beat the Pirates on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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