Knicks vs. Cavaliers Prediction: Cleveland to Win, Donovan Mitchell Projected for Big Game in Wednesday's NBA Matchup [4/2/2025]

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Written by Ryan Leaver

Our expert prediction for Wednesday's New York Knicks vs Cleveland Cavaliers matchup.

New York Knicks-Cleveland Cavaliers Predictions and Game Preview.
Rocket Arena sets the stage for the NBA matchup between the New York Knicks and Cleveland Cavaliers this Wednesday.

NBA action continues on Wednesday at 7:00PM ET as the New York Knicks take on the Cleveland Cavaliers at Rocket Arena.

Based on the latest simulation results and today’s injury reports, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Cavaliers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's New York-Cleveland game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Cavaliers' chance of winning at 79%, with the Knicks at 21%."

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature stars like Donovan Mitchell, Darius Garland and Evan Mobley, while the Knicks will be led by Karl-Anthony Towns, Mikal Bridges and OG Anunoby.

For further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Knicks vs. Cavaliers predictions page.

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Knicks vs. Knicks Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data, we have simulated the result of Wednesday's NBA game between the Knicks and Cavaliers 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Cavaliers a 79% chance of beating the Knicks. Our predicted final score has the Cavaliers winning 120-110.

According to our model, the Knicks (+10.5) have a 53% chance of covering the spread, while the 230.5-point over/under has a 51% chance of staying under.

Pre-Game Probabilities
Last Updated: 11:03PM, Apr 2
Spread
Over / Under
Moneyline
Knicks
Knicks +10.5
53%
47%
Get the best bets with Dimers Pro
See Matchup
Cavaliers
Knicks NYK
Knicks +10.5
53%
47%
See Matchup
Cavaliers CLE
Get the best bets with Dimers Pro

Knicks vs. Cavaliers Odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Knicks Cavaliers
Spread +10.5 (-112) -10.5 (-105)
Moneyline +380 -420
Total o230.5 (-108) u230.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Knicks vs. Cavaliers Picks and Best Bets

Our model's strongest edge in today's Knicks vs. Cavaliers matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best NBA picks and NBA best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Knicks vs. Cavaliers Player Props

Betting on New York vs. Cleveland NBA prop bets? We use the best information available to project how each team's leading players will perform at Rocket Arena.

Karl-Anthony Towns is expected to lead the Knicks in scoring, while Donovan Mitchell is projected to be the top scorer for the Cavaliers.

Donovan Mitchell 2025.
Donovan Mitchell is projected to be one of the top scorers in tonight's game.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game
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Calling Our Shot's Free NBA Picks

Calling Our Shot produces daily NBA betting content, including the best bets featured below.

Knicks vs. Cavs Game-Day Updates and Essential Details

Wednesday's matchup between the Cavaliers and Knicks at Rocket Arena is scheduled to start at 7:00PM ET.

Dimers.com's comprehensive preview of Wednesday's Knicks vs. Cavaliers matchup includes our prediction, picks and the latest betting odds.

Before making any New York vs. Cleveland picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cavaliers, with a 79% win probability, will likely beat the Knicks on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Cavaliers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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