Twins vs. Cardinals Prediction: Minnesota Predicted to Win Saturday's MLB Matchup [3/29/2025]

The St. Louis Cardinals and Minnesota Twins will meet in MLB action at Busch Stadium on Saturday, starting at 2:15PM ET.

The Cardinals will start Erick Fedde (0-0, 0.00 ERA), pitting him against Joe Ryan (0-0, 0.00 ERA) for the Twins.

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Minnesota-St. Louis game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Twins are more likely to win, while the Cardinals have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Twins vs. Cardinals predictions page.

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Twins vs. Twins Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Saturday's MLB game between the Twins and Cardinals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Twins a 52% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 62% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.

Pre-Game Probabilities

Last Updated: 6:28PM, Mar 29

Moneyline

Over / Under

Run Line

Twins

Win %

51%

49%

-110

+100

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Cardinals

Twins MIN

-110

Win %

51%

49%

See Matchup

Cardinals STL

+100

Joe Ryan 0-0, 0.00 ERA

Erick Fedde 0-0, 0.00 ERA

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Twins vs. Cardinals Odds [3/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Twins vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Twins vs. Cardinals matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Twins vs. Cardinals Game-Day Updates and Essential Details

Saturday's MLB game between the Cardinals and Twins at Busch Stadium is scheduled to begin at 2:15PM ET.

• Who: Minnesota Twins vs. St. Louis Cardinals
• Date: Saturday, March 29, 2025
• Time: 2:15PM ET/11:15AM PT
• Venue: Busch Stadium

Dimers.com's full preview of Saturday's Twins vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Minnesota vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Twins, with a 52% win probability, will likely beat the Cardinals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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