Angels vs. Cardinals Prediction: St. Louis Predicted to Win Monday's MLB Matchup [3/31/2025]

The St. Louis Cardinals and Los Angeles Angels will lock horns in MLB action at Busch Stadium on Monday, starting at 7:45PM ET.

Miles Mikolas (0-0, 0.00 ERA) will be the starting pitcher for the Cardinals, while the Angels will counter with Tyler Anderson (0-0, 0.00 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's LA Angels-St. Louis game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Cardinals are likely to win, with a probability of 53%, compared to the Angels' 47%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Angels vs. Cardinals predictions page.

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Angels vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Monday's MLB game between the Angels and Cardinals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Cardinals a 53% chance of defeating the Angels.

According to our model, the Angels (+1.5) have a 65% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.

Pre-Game Probabilities

Last Updated: 11:27PM, Mar 31

Moneyline

Over / Under

Run Line

Angels

Win %

47%

53%

+136

-152

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Cardinals

Angels LAA

+136

Win %

47%

53%

See Matchup

Cardinals STL

-152

Tyler Anderson 0-0, 0.00 ERA

Miles Mikolas 0-0, 0.00 ERA

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Angels vs. Cardinals Odds [3/31/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Angels vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Angels vs. Cardinals matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Angels vs. Cardinals Game-Day Updates and Essential Details

Monday's MLB matchup between the Cardinals and Angels at Busch Stadium is scheduled to commence at 7:45PM ET.

• Who: Los Angeles Angels vs. St. Louis Cardinals
• Date: Monday, March 31, 2025
• Time: 7:45PM ET/4:45PM PT
• Venue: Busch Stadium

Dimers.com's full preview of Monday's Angels vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cardinals, with a 53% win probability, will likely beat the Angels on Monday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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