Guardians vs. Royals Prediction: Kansas City Predicted to Win Saturday's MLB Matchup [3/29/2025]

The Kansas City Royals and Cleveland Guardians will lock horns in MLB action at Kauffman Stadium on Saturday, starting at 4:10PM ET.

Seth Lugo (0-0, 0.00 ERA) will start on the mound for the Royals, pitting him against Gavin Williams (0-0, 0.00 ERA) for the Guardians.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Royals as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Cleveland-Kansas City game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Royals are more likely to win, while the Guardians have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Guardians vs. Royals predictions page.

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Guardians vs. Guardians Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB game between the Guardians and Royals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Royals a 55% chance of beating the Guardians.

According to our model, the over/under total of 8.5 runs has a 51% chance of staying under.

Pre-Game Probabilities

Last Updated: 8:27PM, Mar 29

Moneyline

Over / Under

Run Line

Guardians

Win %

47%

53%

+100

-115

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Royals

Guardians CLE

+100

Win %

47%

53%

See Matchup

Royals KC

-115

Gavin Williams 0-0, 0.00 ERA

Seth Lugo 0-0, 0.00 ERA

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Guardians vs. Royals Odds [3/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Guardians vs. Royals Picks and Best Bets

Our model's strongest edge in today's Guardians vs. Royals matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Guardians vs. Royals Game-Day Updates and Essential Details

Saturday's MLB game between the Royals and Guardians at Kauffman Stadium is scheduled to commence at 4:10PM ET.

• Who: Cleveland Guardians vs. Kansas City Royals
• Date: Saturday, March 29, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Kauffman Stadium

Dimers.com's in-depth preview of Saturday's Guardians vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any Cleveland vs. Kansas City picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Royals, with a 55% win probability, will likely beat the Guardians on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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