White Sox vs. Tigers Prediction: Detroit Predicted to Win Sunday's MLB Matchup [4/6/2025]

MLB action continues on Sunday at 1:40PM ET as the Chicago White Sox square off with the Detroit Tigers at Comerica Park.

The Tigers will start Jackson Jobe (0-0, 6.75 ERA), while the White Sox will counter with Martín Pérez (1-0, 0.00 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Tigers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's CHI White Sox-Detroit game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Tigers with a win probability of 61%, while the White Sox have 39%."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive White Sox vs. Tigers predictions page.

EXCLUSIVE OFFER: Sign up to Dimers Pro with code MARCH today to enjoy a full month for the price of just one week!

Get Your First Month For the Price of 1 Week with Promo Code MARCH

Get Dimers Pro

White Sox vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Sunday's MLB game between the White Sox and Tigers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Tigers a 61% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 58% chance of covering the run line, while the 7.5-run over/under has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 5:28PM, Apr 6

Moneyline

Over / Under

Run Line

White Sox

Win %

39%

61%

+155

-172

Get the best bets with Dimers Pro

See Matchup

Get Dimers Pro

Tigers

White Sox CWS

+155

Win %

39%

61%

See Matchup

Tigers DET

-172

Martín Pérez 1-0, 0.00 ERA

Jackson Jobe 0-0, 6.75 ERA

Get the best bets with Dimers Pro

Get Dimers Pro

White Sox vs. Tigers Odds [4/6/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

White Sox vs. Tigers Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Tigers matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Unlock Every White Sox-Tigers Pick

Get Dimers Pro

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

White Sox vs. Tigers Game-Day Updates and Essential Details

Sunday's MLB action between the Tigers and White Sox at Comerica Park is scheduled to commence at 1:40PM ET.

• Who: Chicago White Sox vs. Detroit Tigers
• Date: Sunday, April 6, 2025
• Time: 1:40PM ET/10:40AM PT
• Venue: Comerica Park

Dimers.com's full preview of Sunday's White Sox vs. Tigers matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Detroit picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Sports Betting Deals Available for Sunday

To make the most of Sunday's big day of sports, headlined by the final round of play at the Valero Texas Openl golf, check out details on the latest Bet365 bonus code "DIMERS" that scores you the choice of two outstanding signup offers. Don't miss out!

Conclusion

We predict the Tigers, with a 61% win probability, will likely beat the White Sox on Sunday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Tigers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.