Cubs vs. Diamondbacks Prediction: Arizona Predicted to Win Saturday's MLB Matchup [3/29/2025]

The Arizona Diamondbacks will face the Chicago Cubs in MLB action at Chase Field on Saturday, starting at 8:10PM ET.

Brandon Pfaadt (0-0, 0.00 ERA) will get the ball for the Diamondbacks, up against Shota Imanaga (0-0, 0.00 ERA) for the Cubs.

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's CHI Cubs-Arizona game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Diamondbacks are more likely to win, while the Cubs have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Cubs vs. Diamondbacks predictions page.

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Cubs vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Saturday's MLB game between the Cubs and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Diamondbacks a 53% chance of defeating the Cubs.

According to our model, the Cubs (+1.5) have a 65% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of staying under.

Pre-Game Probabilities

Last Updated: 12:27AM, Mar 30

Moneyline

Over / Under

Run Line

Cubs

Win %

47%

53%

+104

-118

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D-Backs

Cubs CHC

+104

Win %

47%

53%

See Matchup

D-Backs ARI

-118

Shota Imanaga 0-0, 0.00 ERA

Brandon Pfaadt 0-0, 0.00 ERA

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Cubs vs. Diamondbacks Odds [3/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Diamondbacks Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Diamondbacks matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Cubs vs. Diamondbacks Game-Day Updates and Essential Details

Saturday's MLB game between the Diamondbacks and Cubs at Chase Field is scheduled to begin at 8:10PM ET.

• Who: Chicago Cubs vs. Arizona Diamondbacks
• Date: Saturday, March 29, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Chase Field

Dimers.com's comprehensive preview of Saturday's Cubs vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any CHI Cubs vs. Arizona picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Diamondbacks, with a 53% win probability, will likely beat the Cubs on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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