Angels vs. Cardinals Prediction: St. Louis Predicted to Win Tuesday's MLB Matchup [4/1/2025]

The St. Louis Cardinals and Los Angeles Angels are scheduled to meet in MLB action at Busch Stadium on Tuesday, starting at 7:45PM ET.

Matthew Liberatore (0-0, 0.00 ERA) will start on the mound for the Cardinals, up against Kyle Hendricks (0-0, 0.00 ERA) for the Angels.

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's LA Angels-St. Louis game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Cardinals with a win probability of 57%, compared to 43% for the Angels."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Angels vs. Cardinals predictions page.

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Angels vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Tuesday's MLB matchup between the Angels and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Cardinals a 57% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 61% chance of covering the run line, while the 8-run over/under has a 54% chance of going over.

Pre-Game Probabilities

Last Updated: 11:28PM, Apr 1

Moneyline

Over / Under

Run Line

Angels

Win %

43%

57%

+120

-134

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Cardinals

Angels LAA

+120

Win %

43%

57%

See Matchup

Cardinals STL

-134

Kyle Hendricks 0-0, 0.00 ERA

Matthew Liberatore 0-0, 0.00 ERA

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Angels vs. Cardinals Odds [4/1/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Angels vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Angels vs. Cardinals matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Angels vs. Cardinals Game-Day Updates and Essential Details

Tuesday's MLB action between the Cardinals and Angels at Busch Stadium is scheduled to commence at 7:45PM ET.

• Who: Los Angeles Angels vs. St. Louis Cardinals
• Date: Tuesday, April 1, 2025
• Time: 7:45PM ET/4:45PM PT
• Venue: Busch Stadium

Dimers.com's full preview of Tuesday's Angels vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cardinals, with a 57% win probability, will likely beat the Angels on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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