Yankees vs. Orioles Prediction and Odds - Jul 22, 2022

The Baltimore Orioles take on the New York Yankees in MLB action at Oriole Park at Camden Yards on Friday, starting at 7:05PM ET.

The Orioles will send Tyler Wells (7-5, 3.38 ERA) to the mound, up against Jameson Taillon (10-2, 3.86 ERA) for the Yankees.

Dimers' best betting picks for Yankees vs. Orioles, as well as game predictions and best odds, are featured below.

Who will win Yankees vs. Orioles?

Using trusted machine learning and data, Dimers.com has simulated Friday's Yankees-Orioles MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Yankees a 56% chance of winning against the Orioles.

More: Full Betting Analysis for Yankees vs. Orioles

Yankees vs. Orioles Game Odds

• Run Line: Orioles +1.5 (-120), Yankees -1.5 (+110)
• Moneyline: Orioles +130, Yankees -148
• Total: Over/Under 9 (+105/-115)

Run Line, Moneyline and Over/Under

The Orioles are listed as +1.5 underdogs against the Yankees, with -120 at FanDuel Sportsbook the best odds currently available.

For the favored Yankees (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +110.

DraftKings Sportsbook currently has the best moneyline odds for the Orioles at +130, which means you can bet $100 to profit $130, earning a total payout of $230, if they win.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Yankees at -148, where you can risk $148 to win $100, for a total payout of $248, if they come out on top.

The Over/Under for total runs scored is set at 9 with Caesars Sportsbook, which currently has the best odds for the Over at +105, while DraftKings Sportsbook currently has the best odds for the Under at -115.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 55% chance of covering the run line, while the 9-run Over/Under is a 52% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Yankees vs. Orioles

• Run Line: Orioles +1.5 @ -120 via FanDuel Sportsbook (55% probability)
• Moneyline: Orioles @ +130 via DraftKings Sportsbook (0.5% edge)
• Total: Over 9 @ +105 via Caesars Sportsbook (52% probability)

Dimers' best bets are based on detailed simulations and gambling expertise to help you make better decisions with your state's legal sportsbooks.

While the Yankees are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to being a profitable bettor in the long run.

Yankees vs. Orioles Probabilities

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for NY Yankees vs. Baltimore, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's Yankees-Orioles matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis before Yankees vs. Orioles on Friday July 22, 2022.

Claim Your Risk-Free Bet for Yankees vs. Orioles

Are you looking to bet on NY Yankees vs. Baltimore? Join FanDuel Sportsbook now and get a risk-free first bet up to $1,000, which you can use on Friday's Yankees-Orioles game.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Yankees vs. Orioles. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!

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Yankees vs. Orioles 2022 Game Info

Friday's action between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to commence at 7:05PM ET.

• Who: Baltimore Orioles vs. New York Yankees
• Date: Friday July 22, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Oriole Park at Camden Yards

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What MLB games are on today?

The Yankees and Orioles aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB matchup in our MLB Bet Hub section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.