Yankees vs. Astros Game 2 Prediction - Oct 20, 2022

The Houston Astros face the New York Yankees in Game 2 of the American League Championship Series at Minute Maid Park on Thursday, beginning at 7:37PM ET.

The Astros will send Framber Valdez (0-0, 3.18 ERA) to the mound, while the Yankees will counter with Luis Severino (0-0, 4.76 ERA).

Dimers' top betting picks for Yankees vs. Astros, plus game predictions and best odds, are detailed below.

Who will win Yankees vs. Astros?

Based on advanced machine learning and data, Dimers.com has simulated Thursday's Yankees-Astros MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Astros a 58% chance of getting the W against the Yankees.

More: Yankees vs. Astros Simulated 10K Times

Yankees vs. Astros Game Odds

• Run Line: Astros -1.5 (+158), Yankees +1.5 (-170)
• Moneyline: Astros -141, Yankees +130
• Total: Over/Under 7 (-110/-105)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites versus the Yankees, with +158 at Caesars Sportsbook the best odds currently available.

For the underdog Yankees (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at -170.

Caesars Sportsbook currently has the best moneyline odds for the Astros at -141. That means you can risk $141 to win $100, for a total payout of $241, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Yankees at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under for total runs scored sits at 7 with BetMGM, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Yankees (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 7 runs is a 51% chance of going Over.

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Best Bets for Yankees vs. Astros

• Run Line: Astros -1.5 @ +158 via Caesars Sportsbook (0.1% edge)
• Moneyline: Astros @ -141 via Caesars Sportsbook (58% probability)
• Total: Over 7 @ -110 via BetMGM (51% probability)

Our best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every day of the year.

Although the Yankees are more likely to cover the run line, our best bet of Astros -1.5 is based on the likelihood of that happening, according to DimersBOT, and the top odds available.

Yankees vs. Astros Prediction

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Dimers has full betting coverage of Thursday's Yankees-Astros matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for any changes to our betting analysis before Yankees vs. Astros on Thursday October 20, 2022.

Yankees vs. Astros 2022 Game Info

Thursday's matchup between the Astros and Yankees at Minute Maid Park is scheduled to commence at 7:37PM ET.

• Who: New York Yankees vs. Houston Astros
• Date: Thursday October 20, 2022
• Time: 7:37PM ET / 4:37PM PT
• Venue: Minute Maid Park

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What other MLB games are on today?

Now you've got the 411 on Yankees vs. Astros, get the latest betting analysis for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.