Yankees vs. Astros Computer Picks, MLB Odds and Betting Lines for October 19, 2022

Two heavyweights of the American League suit up for battle in the Championship Series with the Astros looking like the heavy favorites in Game 1.

It's Wednesday, October 19, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.

With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Wednesday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

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Best MLB Bet Today

Yankees vs. Astros, 7:37PM ET

New York dispensed of the Guardians yesterday afternoon with ease to set up the MLB's dream match up with the Astros in the ALCS. The rain delay on Monday was a blessing in disguise for the Yankees who were able to assign Nestor Cortes to the rescheduled series decider over the originally slated pitcher Jameson Taillon who instead gets the nod in Game 1 in Houston. That's significant because Taillon might just be the weak link in this Yankee rotation, and his numbers against the Astros this season would suggest that. In his only season meeting against the World Series favorites on June 23, Taillon gave up 6 ER and two home runs. New York would actually go on to win that game after a 9th-inning rally, but we wouldn't expect a similar scenario here with the Astros given the benefit of a few days off after sweeping the Mariners in the Divisional Series, heading in with their best pitcher in Justin Verlander. This one is set up for an Astros Game 1 domination.

BET: Astros -1.5 (+115). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

Best MLB Prop Today

With two home runs in the ALDS against Seattle, Yordan Alvarez is peaking in form at the right time of year. He heads into Game 1 as one of the key components if the Astros are to advance, and he has some nice form against starting Taillon, hitting him out of the park twice in 6 previous plate appearances. He's a power hitter who knows how to make a statement and he's primed.

BET: Yordan Alvarez 1+ HR (+320). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

⚾️ Yankees vs. Astros Predictions
✍🏼 Betting Preview: Yankees vs. Astros

Visit our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.

Best MLB Same Game Parlay Today

There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $200 no matter what promo to guarantee a big cash.

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🔥 Astros -1.5
🔥 Alvarez HR

*All odds and lines correct at time of publishing