White Sox vs. Guardians Prediction and Odds - Aug 20, 2022

MLB action continues on Saturday at 6:10PM ET as the Chicago White Sox take on the Cleveland Guardians at Progressive Field.

The Guardians will send Shane Bieber (8-6, 3.18 ERA) to the mound, up against Johnny Cueto (5-5, 2.78 ERA) for the White Sox.

Dimers' top betting picks for White Sox vs. Guardians, as well as game predictions and best odds, are detailed below.

Who will win White Sox vs. Guardians?

Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's White Sox-Guardians MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Guardians a 52% chance of getting the W against the White Sox.

More: White Sox vs. Guardians Simulated 10,000 Times

White Sox vs. Guardians Odds

• Run Line: Guardians -1.5 (+130), White Sox +1.5 (-141)
• Moneyline: Guardians -174, White Sox +158
• Total: Over/Under 7.5 (-105/-110)

Run Line, Moneyline and Over/Under

The Guardians are currently -1.5 favorites versus the White Sox, with +130 at DraftKings Sportsbook the best odds currently available.

For the underdog White Sox (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -141.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -174. That means you can risk $174 to win $100, for a total payout of $274, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the White Sox at +158, where you can bet $100 to profit $158, earning a total payout of $258, if they win.

The Over/Under for total runs scored sits at 7.5 with BetMGM, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (-1.5) are a 53% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Free Prop Picks

Best Bets for White Sox vs. Guardians

• Run Line: Guardians -1.5 @ +130 via DraftKings Sportsbook (53% probability) 🔥
• Moneyline: White Sox @ +158 via Caesars Sportsbook (9.2% edge) 🔥
• Total: Over 7.5 @ -105 via BetMGM (54% probability)

Any time you see a 🔥, you know it's one of our best bets of the day across all major pro and college sports.

Dimers' best bets are based on world-class simulations and gambling intelligence to serve you the best possible plays every time.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the White Sox moneyline is the best option due to the 9.2% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers.com is pivotal to being profitable in the long run.

White Sox vs. Guardians Prediction

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Cleveland, and click or tap on See Matchup for more.

Dimers has full betting coverage of Saturday's White Sox-Guardians matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before White Sox vs. Guardians on Saturday August 20, 2022.

Best Sportsbook Promo for White Sox vs. Guardians

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White Sox vs. Guardians 2022 Game Info

Saturday's game between the Guardians and White Sox at Progressive Field is scheduled to begin at 6:10PM ET.

• Who: Cleveland Guardians vs. Chicago White Sox
• Date: Saturday August 20, 2022
• Time: 6:10PM ET / 3:10PM PT
• Venue: Progressive Field

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What other MLB games are on today?

The White Sox and Guardians aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for each and every MLB matchup in our MLB Bet Hub page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.