Nationals vs. Pirates Prediction: Pittsburgh Predicted to Win Tuesday's MLB Matchup [4/15/2025]

The Pittsburgh Pirates will face the Washington Nationals in MLB action at PNC Park on Tuesday, commencing at 6:40PM ET.

The Pirates will send Mitch Keller (1-1, 4.24 ERA) to the mound, pitting him against Jake Irvin (0-0, 5.62 ERA) for the Nationals.

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Washington-Pittsburgh game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Pirates with a win probability of 55%, compared to 45% for the Nationals."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Nationals vs. Pirates predictions page.

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Nationals vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Tuesday's MLB game between the Nationals and Pirates 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Pirates a 55% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 64% chance of covering the run line, while the 8.5-run over/under has a 54% chance of staying under.

Pre-Game Probabilities

Last Updated: 5:28PM, Apr 15

Moneyline

Over / Under

Run Line

Nationals

Win %

45%

55%

+115

-122

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Pirates

Nationals WSH

+115

Win %

45%

55%

See Matchup

Pirates PIT

-122

Jake Irvin 0-0, 5.63 ERA

Mitch Keller 1-1, 4.24 ERA

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Nationals vs. Pirates Odds [4/15/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Pirates Picks and Best Bets

Our model's biggest edge in today's Nationals vs. Pirates matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Nationals vs. Pirates Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Pirates and Nationals at PNC Park is scheduled to start at 6:40PM ET.

• Who: Washington Nationals vs. Pittsburgh Pirates
• Date: Tuesday, April 15, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Tuesday's Nationals vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Washington vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 55% win probability, will likely beat the Nationals on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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