Nationals vs. Pirates Prediction: Pittsburgh Predicted to Win Thursday's MLB Matchup [4/17/2025]

The Pittsburgh Pirates will face the Washington Nationals in MLB action at PNC Park on Thursday, beginning at 12:35PM ET.

The Pirates will have Andrew Heaney (0-1, 3.00 ERA) as their starting pitcher, while the Nationals have opted for Trevor Williams (1-1, 7.36 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's Washington-Pittsburgh game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Pirates with a win probability of 55% and the Nationals with 45%."

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Nationals vs. Pirates predictions page.

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Nationals vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the result of Thursday's MLB matchup between the Nationals and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Pirates a 55% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 64% chance of covering the run line, while the over/under total of 8 runs has a 53% chance of staying under.

Pre-Game Probabilities

Last Updated: 4:28PM, Apr 17

Moneyline

Over / Under

Run Line

Nationals

Win %

45%

55%

+128

-148

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Pirates

Nationals WSH

+128

Win %

45%

55%

See Matchup

Pirates PIT

-148

Trevor Williams 1-1, 7.36 ERA

Andrew Heaney 0-1, 3.00 ERA

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Nationals vs. Pirates Odds [4/17/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Nationals vs. Pirates matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Nationals vs. Pirates Game-Day Updates and Essential Details

Thursday's MLB game between the Pirates and Nationals at PNC Park is scheduled to begin at 12:35PM ET.

• Who: Washington Nationals vs. Pittsburgh Pirates
• Date: Thursday, April 17, 2025
• Time: 12:35PM ET/9:35AM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Thursday's Nationals vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Washington vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 55% win probability, will likely beat the Nationals on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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