Villanova vs. USC Prediction: Villanova Predicted to Win College Basketball Matchup [4/3/2025]

USC and Villanova will meet in college basketball action at MGM Grand Garden Arena on Thursday, with tipoff at 9:30PM ET.

Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) projects Villanova as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's Villanova-USC game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast Villanova with a win probability of 64% and USC with 36%."

For expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Villanova vs. USC predictions page.

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Villanova vs. USC Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and data, we have simulated the outcome of Thursday's NCAA basketball game between Villanova and USC 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model currently gives Villanova a 64% chance of beating USC. Our predicted final score has Villanova winning 77-73.

According to our model, USC (+6.5) has a 61% chance of covering the spread, while the over/under total of 151.5 points has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 1:33AM, Apr 4

Spread

Over / Under

Moneyline

Villanova

USC +6.5

39%

61%

-110

-120

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USC

Villanova VILL

-110

USC +6.5

39%

61%

See Matchup

USC USC

-120

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Villanova vs. USC Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Villanova vs. USC Picks and Best Bets

Our model's strongest edge in today's Villanova vs. USC matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best college basketball picks and college basketball best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Villanova vs. USC Game-Day Updates and Essential Details

Thursday's college basketball game between USC and Villanova at MGM Grand Garden Arena is scheduled to begin at 9:30PM ET.

• Who: Villanova vs. USC
• Date: Thursday, April 3, 2025
• Time: 9:30PM ET/6:30PM PT
• Venue: MGM Grand Garden Arena

Dimers.com's full preview of Thursday's Villanova vs. USC matchup includes our prediction, picks and the latest betting odds.

Before making any Villanova vs. USC picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Conclusion

We predict Villanova, with a 64% win probability, will likely beat USC on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Villanova vs. USC insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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