USC vs. Michigan State March Madness Prediction - Mar 17, 2023

Michigan State takes on USC in March Madness action at Nationwide Arena on Friday, commencing at 12:15PM ET.

Dimers' top betting picks for USC vs. Michigan State, as well as our score prediction and best odds, are featured in this article.

Today's USC vs. Michigan State betting preview is presented by WynnBET, which has a Bet $100, Get $100 Bet Credit offer for new customers.

Who will win USC vs. Michigan State?

Using high-tech machine learning and data, Dimers.com has simulated Friday's USC-Michigan State March Madness matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives Michigan State a 59% chance of defeating USC.

More: USC vs. Michigan State Simulated 10K Times

USC vs. Michigan State Odds

• Spread: Michigan State -2.5 (-110), USC +2.5 (-110)
• Moneyline: Michigan State -138, USC +135
• Total: Over/Under 136.5 (-105/-110)

Point Spread, Moneyline and Over/Under

Michigan State is the -2.5 favorite versus USC, with -110 at PointsBet the best odds currently available.

For the underdog USC (+2.5) to cover the spread, PointsBet also has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for Michigan State at -138, which means you can risk $138 to win $100, for a total payout of $238, if it gets the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for USC at +135, where you can bet $100 to profit $135, earning a total payout of $235, if it wins.

The Over/Under sits at 136.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -105, while PointsBet currently has the best odds for the Under at -110.

As always, make sure you check all of the online sportsbooks available in your state for the best March Madness odds and lines.

According to DimersBOT, Michigan State (-2.5) is a 56% chance of covering the spread, while the 136.5-point Over/Under is a 52% chance of going Under.

More: Track Your Bets via Dimers' Bet Center

Best Bets for USC vs. Michigan State

• Spread: Michigan State -2.5 @ -110 via PointsBet (56% probability)
• Moneyline: Michigan State @ -138 via FanDuel Sportsbook (59% probability)
• Total: Under 136.5 @ -110 via PointsBet (52% probability)

Our best bets are based on complex modeling and gambling intelligence to bring you the best possible plays every day of the year.

USC vs. Michigan State March Madness Prediction

Dimers.com's predicted final score for USC vs. Michigan State at Nationwide Arena on Friday has Michigan State prevailing 70-66.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of Friday's USC-Michigan State matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for any changes to our betting analysis before USC vs. Michigan State on Friday March 17, 2023.

USC vs. Michigan State 2023 March Madness Game Info

Friday's matchup between Michigan State and USC in College Basketball at Nationwide Arena is scheduled to begin at 12:15PM ET.

• Who: USC vs. Michigan State
• Date: Friday March 17, 2023
• Time: 12:15PM ET / 9:15AM PT
• Venue: Nationwide Arena

Looking to join an online sportsbook and start betting on March Madness today? We've listed the best available welcome offers for each legal betting state.

Want more CBB predictions like this?

So, you liked our USC vs. Michigan State betting predictions? Awesome. Did you know our College Basketball Betting News page has a detailed betting preview for every CBB game as soon as the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets, which allows us to create the most accurate CBB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

While you're here, Dimers' NCAA Basketball Futures page is our in-house approach to determining who will win March Madness, with our data-led probabilities matched against the best odds on the market.