UCLA vs. Southern California CFB Predictions and Odds - Nov 20, 2021

Southern California faces UCLA in College Football Week 12 action at Los Angeles Memorial Coliseum on Saturday, beginning at 4:00 PM EST.

Dimers' best betting picks for UCLA vs. Southern California, plus game predictions and best odds, are featured in this article.

Who will win UCLA vs. Southern California?

Based on high-tech machine learning and data, Dimers.com has simulated Saturday's UCLA-Southern California NCAA Football matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives UCLA a 54% chance of defeating Southern California.

MORE: Full betting guide for UCLA vs. Southern California

UCLA vs. Southern California Point Spread, Moneyline and Over/Under

Southern California is the +5.5 underdog against UCLA, with -114 at FanDuel Sportsbook the best odds available.

For the favored UCLA (-5.5) to cover the spread, FanDuel Sportsbook also has the best odds on offer at -106.

FanDuel Sportsbook has the best moneyline odds for Southern California at +172. That means you can bet $100 to profit $172, earning a total payout of $272, if it wins.

Elsewhere, Caesars Sportsbook has the best moneyline odds for UCLA at -175, where you can risk $175 to win $100, for a total payout of $275, if it comes out on top.

The Over/Under for total points scored sits at 65.5 with Caesars Sportsbook, which has the best odds for the Over at -110, while PointsBet has the best odds for the Under at -105.

As always, make sure you check all the legal sportbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Southern California (+5.5) is a 63% chance of covering the spread, while the Over/Under total of 65.5 points is a 52% chance of going Over.

MORE: Predictions and best bets for every College Football matchup

Best Bets for UCLA vs. Southern California

• Spread: Southern California +5.5 at -114 with FanDuel Sportsbook (63% probability) 🔥
• Moneyline: Southern California Win at +172 with FanDuel Sportsbook (9.0% edge) 🔥
• Over/Under: Over 65.5 at -110 with Caesars Sportsbook (52% probability)

If you see a 🔥, that means it's one of our best bets today across all sports.

While UCLA is more likely to win the game, according to DimersBOT, taking Southern California moneyline is the best option due to the 9.0% edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published on Dimers.com is crucial to achieving long-term profitability.

UCLA vs. Southern California Score Prediction

Dimers.com's predicted final score for UCLA vs. Southern California at Los Angeles Memorial Coliseum on Saturday has UCLA winning 33-31.

Dimers has full betting coverage of this week's UCLA-Southern California game, including pre-game predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep checking this article for the latest before UCLA vs. Southern California on Saturday November 20, 2021.

UCLA vs. Southern California 2021 CFB Game Info

When does Southern California play UCLA in College Football?

• Date: Saturday November 20, 2021
• Time: 4:00 PM EST / 1:00 PM PST
• Venue: Los Angeles Memorial Coliseum

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