Tottenham vs. Southampton Prediction, Odds, Premier League Picks [4/6/2025]

Tottenham will square off with Southampton in Premier League action at Tottenham Hotspur Stadium on Sunday, commencing at 9:00AM ET.

Based on updated simulation results, Dimers' advanced Premier League model (see Dimers Pro for full access) projects Tottenham as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Tottenham-Southampton game," said Jason Bevilacqua from Dimers.

"After incorporating the most recent updates and numerous additional inputs, our prediction gives Tottenham a 68.6% chance of winning, Southampton a 13.7% chance, and a 17.7% chance of a draw."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Tottenham vs. Southampton predictions page.

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Tottenham vs. Southampton Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the result of Sunday's Premier League match between Tottenham and Southampton 10,000 times as part of our Premier League predictions coverage.

Our leading predictive model suggests a 68.6% chance of Tottenham winning, a 13.7% chance for Southampton, and a 17.7% chance of a draw.

Tottenham vs. Southampton Odds

We have researched the best Premier League odds in America for this game, which are listed here:

Market	Tottenham	Southampton	Draw
Moneyline	-250	+625	+425

All odds are correct at the time of publication and are subject to change.

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Tottenham vs. Southampton Picks and Best Bets

Our model's biggest edge in today's Tottenham vs. Southampton matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best Premier League picks and Premier League best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Tottenham vs. Southampton: Correct Score and BTTS Predictions

The top three most likely final scores, according to our model, are listed below, with a 2-0 Tottenham win being the most probable:

Final Score	Probability
TOT 2-0 SOU	10%
TOT 2-1 SOU	9.6%
TOT 1-0 SOU	8.4%

When it comes to the both teams to score (BTTS) market, we project a 56.2% chance of the yes hitting, and a 43.8% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations.

Tottenham vs. Southampton Game-Day Updates and Essential Details

Sunday's Premier League matchup between Tottenham and Southampton at Tottenham Hotspur Stadium is scheduled to start in the United States at 9:00AM ET.

• Who: Tottenham vs. Southampton
• Date: Sunday, April 6, 2025
• Time: 9:00AM ET/6:00AM PT
• Venue: Tottenham Hotspur Stadium

Dimers.com's full preview of Sunday's Tottenham vs. Southampton matchup includes our prediction, picks and the latest betting odds.

Before making any Southampton vs. Tottenham picks, be sure to check out the latest Premier League predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, Tottenham has a 68.6% win probability on Sunday, Southampton has a 13.7% win probability, and there is a 17.7% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Tottenham vs. Southampton insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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