Titans vs. Colts Week 4 Prediction and Odds - Oct 2, 2022

The Indianapolis Colts take on the Tennessee Titans in NFL Week 4 action at Lucas Oil Stadium on Sunday, beginning at 1:00PM ET.

Dimers' free betting picks for Titans vs. Colts, as well as game predictions, betting odds and touchdown scorer probabilities, are detailed in this article.

This Tennessee vs. Indianapolis betting analysis is brought to you by FanDuel Sportsbook, which is currently offering an outstanding No Sweat First Bet bonus up to $1,000 for new users.

Who will win Titans vs. Colts?

Using trusted machine learning and data, Dimers.com has simulated Sunday's Titans-Colts NFL game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Colts a 65% chance of defeating the Titans in Week 4 of the NFL season.

More: Titans vs. Colts Simulated 10,000 Times

Titans vs. Colts Current Odds

• Spread: Colts -4.5 (-105), Titans +4.5 (-107)
• Moneyline: Colts -190, Titans +175
• Total: Over/Under 43 (-105/-110)

Point Spread, Moneyline and Over/Under

The Colts are -4.5 favorites versus the Titans, with -105 at DraftKings Sportsbook the best odds currently available.

For the underdog Titans (+4.5) to cover the spread, PointsBet has the best odds currently on offer at -107.

BetMGM currently has the best moneyline odds for the Colts at -190, which means you can risk $190 to win $100, for a total payout of $290, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Titans at +175, where you can put down $100 to profit $175, earning a total payout of $275, if they win.

The Over/Under for total points scored sits at 43 with PointsBet, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the Titans (+4.5) are a 54% chance of covering the spread, while the Over/Under total of 43 points is a 56% chance of going Over.

More: Predictions for Every NFL Week 4 Game

Best Bets for Titans vs. Colts

• Spread: Titans +4.5 @ -107 via PointsBet (54% probability)
• Moneyline: Colts @ -190 via BetMGM (65% probability)
• Total: Over 43 @ -105 via PointsBet (56% probability) 🔥

When you see a 🔥, that means it's one of our best bets of the day across any sport.

Dimers' best bets are based on detailed simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in your state.

Titans vs. Colts Prediction

Dimers.com's predicted final score for Tennessee vs. Indianapolis at Lucas Oil Stadium in Week 4 has the Colts winning 23-20.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's Titans-Colts matchup in Week 4, including pregame predictions, best betting picks, and live win probabilities.

Titans vs. Colts Player Props

Who will score the first touchdown in Titans vs. Colts? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Titans and Colts, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop picks for Sunday's game.

According to DimersBOT, Indianapolis' Jonathan Taylor is most likely to score the first TD in Titans vs. Colts.

DimersBOT gives Taylor a 15.7% chance of scoring the first TD at Lucas Oil Stadium, while the Colts RB is a 57.6% chance of scoring an anytime touchdown.

Scroll down for our full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Tennessee Titans

• Derrick Henry: 14.4% probability
• Robert Woods: 7.6% probability
• Treylon Burks: 6.6% probability
• Ryan Tannehill: 3.5% probability
• Geoff Swaim: 3.4% probability

Indianapolis Colts

• Jonathan Taylor: 15.7% probability
• Michael Pittman: 8.9% probability
• Nyheim Hines: 6.6% probability
• Alec Pierce: 4.9% probability
• Kylen Granson: 4.7% probability

Anytime Touchdown Scorer Probabilities

Tennessee Titans

• Derrick Henry: 53.3% probability
• Robert Woods: 32.1% probability
• Treylon Burks: 28.7% probability
• Ryan Tannehill: 17.0% probability
• Geoff Swaim: 16.3% probability

Indianapolis Colts

• Jonathan Taylor: 57.6% probability
• Michael Pittman: 36.7% probability
• Nyheim Hines: 29.7% probability
• Alec Pierce: 22.2% probability
• Kylen Granson: 20.2% probability

Titans-Colts Projected Player Stats

Of the starting quarterbacks, the Titans' Ryan Tannehill is projected for 217 passing yards, while the Colts' Matt Ryan is expected to throw for a whopping 277 yards.

Titans Starting QB

• Ryan Tannehill: 217 projected yards

Colts Starting QB

• Matt Ryan: 277 projected yards

Titans Rushing

• Derrick Henry: 82 projected yards
• Ryan Tannehill: 14 projected yards
• Dontrell Hilliard: 13 projected yards

Colts Rushing

• Jonathan Taylor: 110 projected yards
• Nyheim Hines: 19 projected yards
• Matt Ryan: 8 projected yards

Titans Receiving

• Treylon Burks: 45 projected yards
• Robert Woods: 45 projected yards
• Austin Hooper: 31 projected yards
• Kyle Philips: 31 projected yards
• Nick Westbrook-Ikhine: 20 projected yards

Colts Receiving

• Michael Pittman: 63 projected yards
• Alec Pierce: 36 projected yards
• Jonathan Taylor: 29 projected yards
• Nyheim Hines: 27 projected yards
• Parris Campbell: 25 projected yards

Remember, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Titans vs. Colts on Sunday October 2, 2022.

Titans vs. Colts 2022

The NFL Week 4 matchup between the Colts and Titans at Lucas Oil Stadium is scheduled to commence at 1:00PM ET.

• Who: Tennessee Titans vs. Indianapolis Colts
• Date: Sunday October 2, 2022
• Time: 1:00PM ET / 10:00AM PT
• Venue: Lucas Oil Stadium

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