Tigers vs. White Sox Prediction and Odds - Sep 23, 2022

The Chicago White Sox and Detroit Tigers are scheduled to meet in MLB at Guaranteed Rate Field on Friday, starting at 8:10PM ET.

The White Sox will have Lucas Giolito (10-9, 5.07 ERA) start, pitting him against Eduardo Rodriguez (3-5, 4.36 ERA) for the Tigers.

Dimers' top betting picks for Tigers vs. White Sox, plus game predictions and best odds, are featured in this article.

Who will win Tigers vs. White Sox?

Using trusted machine learning and data, Dimers.com has simulated Friday's Tigers-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the White Sox a 63% chance of beating the Tigers.

More: Tigers vs. White Sox Simulated 10K Times

Tigers vs. White Sox Current Odds

• Run Line: White Sox -1.5 (+125), Tigers +1.5 (-140)
• Moneyline: White Sox -175, Tigers +152
• Total: Over/Under 7.5 (+100/+100)

Run Line, Moneyline and Over/Under

The White Sox are -1.5 favorites versus the Tigers, with +125 at DraftKings Sportsbook the best odds currently available.

For the underdog Tigers (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -140.

DraftKings Sportsbook currently has the best moneyline odds for the White Sox at -175, which means you can risk $175 to win $100, for a total payout of $275, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Tigers at +152, where you can bet $100 to profit $152, earning a total payout of $252, if they win.

The Over/Under for total runs scored sits at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while Caesars Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Tigers (+1.5) are a 56% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Tigers vs. White Sox

• Run Line: White Sox -1.5 @ +125 via DraftKings Sportsbook
• Moneyline: White Sox @ -175 via DraftKings Sportsbook (63% probability)
• Total: Over 7.5 @ +100 via DraftKings Sportsbook (52% probability)

Our best bets are based on detailed simulations and betting expertise to help you make more informed investments with the legal sportsbooks in America.

Although the Tigers are more likely to cover the run line, our best bet of White Sox -1.5 is based on the likelihood of that happening, according to DimersBOT, and the top odds available.

Tigers vs. White Sox Prediction

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Tigers-White Sox matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for the latest betting insights ahead of Tigers vs. White Sox on Friday September 23, 2022.

Tigers vs. White Sox 2022 Game Info

Friday's game between the White Sox and Tigers at Guaranteed Rate Field is scheduled to commence at 8:10PM ET.

• Who: Detroit Tigers vs. Chicago White Sox
• Date: Friday September 23, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Guaranteed Rate Field

Want to join an online sportsbook and start betting on MLB? Check out the best sportsbook promos in your state.

What other MLB games are on today?

The Tigers and White Sox aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for each and every MLB game via our MLB Predictions section.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.