Tennessee Titans vs. Indianapolis Colts Early Predictions for NFL Week 16: Odds, Picks and Preview [2024]

The Indianapolis Colts and Tennessee Titans will lock horns in Week 16 of the NFL season at Lucas Oil Stadium on Sunday, December 22, 2024, with kickoff set for 1:00PM ET.

Early simulation results from Dimers' advanced NFL model project the Colts as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Titans vs. Colts predictions page.

Titans vs. Colts Week 16 Details

The NFL Week 16 game between the Colts and Titans at Lucas Oil Stadium is scheduled for December 22, 2024.

• Who: Tennessee Titans vs. Indianapolis Colts
• Date: Sunday, December 22, 2024
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium

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Titans vs. Colts Opening Odds

We've researched the best betting odds across America for this Week 16 game, detailed below:

• Spread: Titans +4 (-110), Colts -4 (-110)
• Moneyline: Titans +160, Colts -192
• Total: Over/Under 45.5 (-108/-112)

Tennessee vs. Indianapolis Early Predictions

Leveraging trusted machine learning and analysis, we have simulated the Titans vs. Colts game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Titans 36%, Colts 64%
• Predicted Final Score: Titans 20-24 Colts
• Spread: Titans (+4) 50%, Colts (-4) 50%
• Total Points (45.5): Over 45%, Under 55%

As of December 15, 2024, these Titans-Colts predictions reflect the latest data and insights available.

Conclusion

We predict the Colts, with a 64% win probability, will likely beat the Titans in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Titans vs. Colts game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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