TCU vs. Iowa State CFB Predictions and Odds - Nov 26, 2021

Iowa State squares off with TCU in College Football Week 13 action at Jack Trice Stadium on Friday, beginning at 4:30 PM EST.

Dimers' free betting picks for TCU vs. Iowa State, as well as game predictions and best odds, are detailed below.

Who will win TCU vs. Iowa State?

Based on high-tech machine learning and data, Dimers.com has simulated Friday's TCU-Iowa State NCAA Football game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives Iowa State an 80% chance of defeating TCU.

MORE: TCU vs. Iowa State Simulated 10,000 Times

TCU vs. Iowa State Point Spread, Moneyline and Over/Under

Iowa State is listed as the -15 favorite against TCU, with -115 at DraftKings Sportsbook the best odds available.

For the underdog TCU (+15) to cover the spread, DraftKings Sportsbook also has the best odds on the market at -105.

PointsBet has the best moneyline odds for Iowa State at -680, which means you can risk $680 to win $100, for a total payout of $780, if it gets the W.

Meanwhile, DraftKings Sportsbook has the best moneyline odds for TCU at +500, where you can bet $100 to profit $500, earning a total payout of $600, if it wins.

The Over/Under sits at 60.5 with FanDuel Sportsbook, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check all the online sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, TCU (+15) is a 51% chance of covering the spread, while the 60.5-point Over/Under is a 52% chance of going Over.

MORE: Predictions for Every CFB Game

Best Bets for TCU vs. Iowa State

• Spread: TCU +15 at -105 with DraftKings Sportsbook (51% probability)
• Moneyline: TCU Win at +500 with DraftKings Sportsbook (3.2% edge)
• Over/Under: Over 60.5 at -110 with FanDuel Sportsbook (52% probability)

While Iowa State is more likely to win the game, according to DimersBOT, betting on TCU moneyline is the best option because of the 3.2% edge identified when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges published here at Dimers is pivotal to achieving long-term profitability as a bettor.

TCU vs. Iowa State Score Prediction

Dimers.com's predicted final score for TCU vs. Iowa State at Jack Trice Stadium on Friday has Iowa State winning 37-23.

Use our dynamic widget below to view the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's TCU-Iowa State matchup, including pre-game predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so refresh this page for any changes to our betting insights before TCU vs. Iowa State on Friday November 26, 2021.

TCU vs. Iowa State 2021 CFB Game Info

When does Iowa State play TCU in College Football?

• Date: Friday November 26, 2021
• Time: 4:30 PM EST / 1:30 PM PST
• Venue: Jack Trice Stadium

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