Syracuse vs. Clemson CFB Prediction and Odds - Oct 22, 2022

Clemson faces Syracuse in College Football action at Memorial Stadium on Saturday, with kickoff at 12:00PM ET.

Dimers' free betting picks for Syracuse vs. Clemson, as well as game predictions and betting odds, are featured below.

Who will win Syracuse vs. Clemson?

Using cutting-edge computer power and data, Dimers.com has simulated Syracuse vs. Clemson 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives Clemson a 77% chance of defeating Syracuse.

More: Syracuse vs. Clemson Simulated 10,000 Times

Syracuse vs. Clemson Odds

• Spread: Clemson -14 (-107), Syracuse +14 (-107)
• Moneyline: Clemson -575, Syracuse +450
• Total: Over/Under 50 (-107/-107)

Point Spread, Moneyline and Over/Under

Clemson is currently the -14 favorite against Syracuse, with -107 at PointsBet the best odds currently available.

For the underdog Syracuse (+14) to cover the spread, PointsBet also has the best odds currently on offer at -107.

PointsBet currently has the best moneyline odds for Clemson at -575, which means you can risk $575 to win $100, for a total payout of $675, if it gets the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for Syracuse at +450, where you can bet $100 to profit $450, earning a total payout of $550, if it wins.

The Over/Under sits at 50 with PointsBet, which currently has the best odds for the Over at -107, as well as the best odds for the Under at -107.

As always, make sure you check all of the legal sportbooks that are available in your state for the best College Football odds and lines.

According to DimersBOT, Syracuse (+14) is a 56% chance of covering the spread, while the 50-point Over/Under is considered an equal 50-50 chance of hitting.

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Best Bets for Syracuse vs. Clemson

• Spread: Syracuse +14 @ -107 via PointsBet (56% probability) 🔥
• Moneyline: Syracuse @ +450 via DraftKings Sportsbook (5.1% edge) 🔥
• Total: Under 50 @ -107 via PointsBet (50% probability)

Any time you see a 🔥, that means it's one of Dimers' best free picks of the day across all major pro and college sports.

Dimers' best bets are based on complex modeling and betting intelligence to help you make more informed investments with the legal sportsbooks in the USA.

While Clemson is more likely to win the game, according to DimersBOT, betting on Syracuse moneyline is the best option due to the 5.1% edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers.com is pivotal to achieving long-term profitability as a bettor.

Syracuse vs. Clemson Prediction

Dimers.com's predicted final score for Syracuse vs. Clemson at Memorial Stadium on Saturday has Clemson winning 29-19.

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Syracuse-Clemson matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates frequently, so refresh this page for the latest betting analysis before Syracuse vs. Clemson on Saturday October 22, 2022.

Syracuse vs. Clemson 2022 CFB Game Info

Saturday's matchup between Clemson and Syracuse in College Football at Memorial Stadium is scheduled to commence at 12:00PM ET.

• Who: Syracuse vs. Clemson
• Date: Saturday October 22, 2022
• Time: 12:00PM ET / 9:00AM PT
• Venue: Memorial Stadium

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What other College Football games are on this week?

Now you've got the 411 on Syracuse vs. Clemson, take a look at the latest betting coverage for all upcoming NCAA Football games in our College Football Bet Hub, where you can find probabilities and odds, plus our best bets for every single CFB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!