Southern Methodist vs. Cincinnati CFB Predictions and Odds - Nov 20, 2021

College Football Week 12 action continues on Saturday at 3:30 PM EST as Southern Methodist takes on the favored Cincinnati at Nippert Stadium.

Dimers' top betting picks for Southern Methodist vs. Cincinnati, as well as game predictions and best odds, are featured in this article.

Who will win Southern Methodist vs. Cincinnati?

Using advanced machine learning and data, Dimers.com has simulated Saturday's Southern Methodist-Cincinnati NCAA Football matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives Cincinnati a 67% chance of beating Southern Methodist.

MORE: Southern Methodist vs. Cincinnati simulated 10,000 times

Southern Methodist vs. Cincinnati Point Spread, Moneyline and Over/Under

Cincinnati is the -11.5 favorite at home to Southern Methodist, with -110 at FanDuel Sportsbook the best odds available.

For the underdog Southern Methodist (+11.5) to cover the spread, FanDuel Sportsbook also has the best odds on offer at -110.

DraftKings Sportsbook has the best moneyline odds for Cincinnati at -380, which means you can risk $380 to win $100, for a total payout of $480, if it gets the W.

On the other hand, Caesars Sportsbook has the best moneyline odds for Southern Methodist at +310, where you can put down $100 to profit $310, earning a total payout of $410, if it wins.

The Over/Under for total points scored is set at 65.5 with PointsBet, which has the best odds for the Over at -105, while FanDuel Sportsbook has the best odds for the Under at -108.

As always, check out the sportsbooks you can bet with in your state for the best College Football odds and lines.

According to DimersBOT, Southern Methodist (+11.5) is a 55% chance of covering the spread, while the Over/Under total of 65.5 points is considered an equal 50-50 chance of hitting.

MORE: Predictions for every College Football Week 12 matchup

Best Bets for Southern Methodist vs. Cincinnati

• Spread: Southern Methodist +11.5 at -110 with FanDuel Sportsbook (55% probability)
• Moneyline: Southern Methodist Win at +310 with Caesars Sportsbook (8.7% edge) 🔥
• Over/Under: Over 65.5 at -105 with PointsBet (50% probability)

When you see a 🔥, you know it's one of our best free picks today across all major pro and college sports.

While Cincinnati is more likely to win the game, according to DimersBOT, taking Southern Methodist moneyline is the best option due to the 8.7% edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published on Dimers.com is crucial to being profitable in the long run.

Southern Methodist vs. Cincinnati Score Prediction

Dimers.com's predicted final score for Southern Methodist vs. Cincinnati at Nippert Stadium this Saturday has Cincinnati winning 36-28.

Dimers has full coverage of this week's Southern Methodist-Cincinnati matchup, including pre-game predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this page for any changes before Southern Methodist vs. Cincinnati on Saturday November 20, 2021.

Southern Methodist vs. Cincinnati 2021 CFB Game Info

When does Cincinnati play Southern Methodist in College Football?

• Date: Saturday November 20, 2021
• Time: 3:30 PM EST / 12:30 PM PST
• Venue: Nippert Stadium

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We use the power of predictive analytics to find edges in the markets so we can publish the best CFB betting previews available. We're able to do this by comparing our unique and accurate probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.