South Carolina vs. Clemson CFB Prediction and Odds - Nov 26, 2022

Clemson faces South Carolina in College Football action at Memorial Stadium on Saturday, commencing at 12:00PM ET.

Dimers' best betting picks for South Carolina vs. Clemson, plus game predictions and best odds, are detailed in this article.

Who will win South Carolina vs. Clemson?

Using high-tech machine learning and data, Dimers.com has simulated South Carolina vs. Clemson 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives Clemson an 82% chance of defeating South Carolina.

More: South Carolina vs. Clemson Simulated 10,000 Times

South Carolina vs. Clemson Game Odds

• Spread: Clemson -14 (-110), South Carolina +14 (-105)
• Moneyline: Clemson -588, South Carolina +470
• Total: Over/Under 53.5 (-108/-110)

Point Spread, Moneyline and Over/Under

Clemson is the -14 favorite versus South Carolina, with -110 at Caesars Sportsbook the best odds currently available.

For the underdog South Carolina (+14) to cover the spread, DraftKings Sportsbook has the best odds currently on the market at -105.

Caesars Sportsbook currently has the best moneyline odds for Clemson at -588. That means you can risk $588 to win $100, for a total payout of $688, if it gets the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for South Carolina at +470, where you can bet $100 to profit $470, earning a total payout of $570, if it wins.

The Over/Under is set at 53.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -108, while DraftKings Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, South Carolina (+14) is a 52% chance of covering the spread, while the 53.5-point Over/Under is a 55% chance of going Under.

More: Best Prop Bets Today

Best Bets for South Carolina vs. Clemson

• Spread: South Carolina +14 @ -105 via DraftKings Sportsbook (52% probability)
• Moneyline: South Carolina @ +470 via DraftKings Sportsbook (0.1% edge)
• Total: Under 53.5 @ -110 via DraftKings Sportsbook (55% probability)

Our best bets are based on detailed simulations and wagering intelligence to help you make more informed investments with your state's legal sportsbooks.

While Clemson is more likely to win the game, according to DimersBOT, taking South Carolina moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers.com is pivotal to being a profitable bettor in the long run.

South Carolina vs. Clemson Prediction

Dimers.com's predicted final score for South Carolina vs. Clemson at Memorial Stadium this Saturday has Clemson winning 32-18.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's South Carolina-Clemson matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this article for any changes to our betting insights ahead of South Carolina vs. Clemson on Saturday November 26, 2022.

South Carolina vs. Clemson 2022 CFB Game Info

Saturday's matchup between Clemson and South Carolina in College Football at Memorial Stadium is scheduled to commence at 12:00PM ET.

• Who: South Carolina vs. Clemson
• Date: Saturday November 26, 2022
• Time: 12:00PM ET / 9:00AM PT
• Venue: Memorial Stadium

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Want more CFB predictions like this?

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We use the power of predictive analytics to find edges in the markets so we can write the best CFB betting previews available. We're able to do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.