SIUE vs. Houston Prediction: Houston Predicted to Win March Madness First Round Matchup [3/20/2025]

Houston and SIUE are scheduled to meet in March Madness First Round action at INTRUST Bank Arena on Thursday, starting at 2:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Houston as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities from our expert team.

"Using the latest data, our experts simulated Thursday's SIUE-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast Houston with a win probability of 99% and SIU-Edwardsville with 1%."

For a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive SIUE vs. Houston predictions page.

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SIUE vs. Houston Prediction: Who Will Win and Advance to the Second Round?

Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's NCAA Tournament matchup between SIUE and Houston 10,000 times as part of our March Madness predictions coverage.

Our independent predictive model currently gives Houston a 99% chance of beating SIU-Edwardsville. Our predicted final score has Houston winning 79-52.

According to our model, SIU-Edwardsville (+28.5) has a 53% chance of covering the spread, while the over/under total of 128.5 points has a 55% chance of going over.

Pre-Game Probabilities

Last Updated: 5:33PM, Mar 20

Spread

Over / Under

Moneyline

SIU-Edwardsville

SIU-Edwardsville +29.0

54%

46%

-109

-112

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See Matchup

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Houston

SIU-Edwardsville SIUE

-109

SIU-Edwardsville +29.0

54%

46%

See Matchup

Houston HOU

-112

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SIUE vs. Houston March Madness Odds

We have researched the best March Madness odds in America for this First Round game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boost your betting this month with the top March Madness betting sites and March Madness betting promos, sourced from top sportsbooks and DFS operators.

SIUE vs. Houston Picks and Best Bets

Our model's biggest edge in today's SIUE vs. Houston matchup is on the spread.

Our expert predictions, matched against the best odds, reveal the best March Madness picks and March Madness best bets for every game throughout the tournament.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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SIUE vs. Houston Game-Day Updates and Essential Details

Thursday's college basketball game between Houston and SIUE at INTRUST Bank Arena is scheduled to start at 2:00PM ET.

• Who: SIU-Edwardsville vs. Houston
• Date: Thursday, March 20, 2025
• Time: 2:00PM ET/11:00AM PT
• Venue: INTRUST Bank Arena
• March Madness Stage: First Round

Dimers.com's in-depth preview of Thursday's SIUE vs. Houston matchup includes our prediction, picks and the latest betting odds.

Before making any SIUE vs. Houston picks, be sure to check out the latest March Madness predictions and betting advice from Dimers Pro.

Key March Madness Guides and Insights

• Learn about NCAA Championship history and the lowest-seeded team to ever win March Madness
• Get answers to legal questions, including which states you can legally bet on college sports and the minimum age required to place a bet on March Madness
• A breakdown of March Madness futures bets and popular prop bets for the NCAA tournament
• Explore strategy with guides on identifying value bets during the tournament and betting on individual player awards like Tournament MVP
• Understand the tournament format, including how many games are played in March Madness and how venue locations impact teams when playing at neutral sites

Conclusion

We predict Houston, with a 99% win probability, will likely beat SIU-Edwardsville on Thursday.

AI and automation have enhanced this article to quickly deliver accurate SIU-Edwardsville vs. Houston insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on College Basketball

Keep up with the latest college basketball predictions, college basketball news and NCAA Tournament parlay picks throughout the tournament. Plus, our NCAA Tournament Championship odds offer the latest probabilities for every March Madness contender.