Mariners vs. Reds Prediction: Cincinnati Predicted to Win Tuesday's MLB Matchup [4/15/2025]

The Cincinnati Reds will take on the Seattle Mariners, in what is expected to be a tight MLB game, at Great American Ball Park on Tuesday, starting at 6:40PM ET.

The Reds will have Nick Lodolo (2-1, 0.96 ERA) as their starting pitcher, up against Luis Castillo (1-1, 2.12 ERA) for the Mariners.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Reds as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Seattle-Cincinnati game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Reds with a win probability of 53%, compared to 47% for the Mariners."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Mariners vs. Reds predictions page.

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Mariners vs. Mariners Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the result of Tuesday's MLB matchup between the Mariners and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Reds a 53% chance of defeating the Mariners.

According to our model, the Reds (+1.5) have a 64% chance of covering the run line, while the over/under total of 8.5 runs has an equal 50-50 chance of hitting.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 15

Moneyline

Over / Under

Run Line

Mariners

Win %

47%

53%

-115

+136

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Reds

Mariners SEA

-115

Win %

47%

53%

See Matchup

Reds CIN

+136

Luis Castillo 1-1, 2.12 ERA

Nick Lodolo 2-1, 0.96 ERA

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Mariners vs. Reds Odds [4/15/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Reds Picks and Best Bets

Our model's strongest edge in today's Mariners vs. Reds matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Mariners vs. Reds Game-Day Updates and Essential Details

Tuesday's MLB game between the Reds and Mariners at Great American Ball Park is scheduled to begin at 6:40PM ET.

• Who: Seattle Mariners vs. Cincinnati Reds
• Date: Tuesday, April 15, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Great American Ball Park

Dimers.com's full preview of Tuesday's Mariners vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Seattle vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Reds, with a 53% win probability, will likely beat the Mariners on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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