San Luis vs. Mazatlan Prediction, Odds, Liga MX Picks [4/5/2025]

Atletico San Luis will face Mazatlan in the Liga MX playoffs at Estadio Alfonso Lastras Ramírez on Saturday, starting at 9:00PM ET.

Based on updated simulations, Dimers' proven Liga MX model (see Dimers Pro for full access) predicts San Luis as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's San Luis-Mazatlan game," said Dave Garofolo from Dimers.

"Taking into account the most current updates and numerous additional factors, our prediction gives Atletico San Luis a 46.2% chance of winning, Mazatlan a 27.9% chance, and a 25.8% chance of a draw."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Atletico San Luis vs. Mazatlan predictions page.

EXCLUSIVE OFFER: Sign up to Dimers Pro with code MARCH today to enjoy a full month for the price of just one week!

Atletico San Luis vs. Mazatlan Prediction: Who Will Win?

Using powerful machine learning and data analysis, we have simulated the result of Saturday's Liga MX matchup between Atletico San Luis and Mazatlan 10,000 times as part of our Liga MX predictions coverage.

Our independent predictive model indicates a 46.2% chance of Atletico San Luis winning, a 27.9% chance for Mazatlan, and a 25.8% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 52% chance of staying under, according to our model.

Atletico San Luis vs. Mazatlan Odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Atletico San Luis	Mazatlan	Draw
+105	+240	+260

Total Goals

Over 2.5	Under 2.5
-120	-110

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Atletico San Luis vs. Mazatlan Picks and Best Bets

Our model's strongest edge in today's Atletico San Luis vs. Mazatlan matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Atletico San Luis vs. Mazatlan: Correct Score and BTTS Predictions

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

Final Score	Probability
ASL 1-1 MZA	12.3%
ASL 1-0 MZA	11.2%
ASL 2-1 MZA	9.2%

When it comes to the both teams to score (BTTS) market, we project a 51.7% chance of the yes hitting, and a 48.3% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations, meaning the most likely correct score can differ from our predicted winner.

San Luis vs. Mazatlan Game-Day Updates and Essential Details

Saturday's action between Atletico San Luis and Mazatlan at Estadio Alfonso Lastras Ramírez is scheduled to start at 9:00PM ET.

• Who: Atletico San Luis vs. Mazatlan
• Date: Saturday, April 5, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Estadio Alfonso Lastras Ramírez

Dimers.com's in-depth preview of Saturday's Atletico San Luis vs. Mazatlan matchup includes our prediction, picks and the latest betting odds.

Before making any Mazatlan vs. San Luis picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Atletico San Luis has a 46.2% win probability on Saturday, Mazatlan has a 27.9% win probability, and there is a 25.8% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Atletico San Luis vs. Mazatlan insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on Liga MX

Stay informed with the latest Liga MX betting news and parlay picks throughout the season.