Giants vs. Phillies Prediction: Philadelphia Predicted to Win Tuesday's MLB Matchup [4/15/2025]

The Philadelphia Phillies and San Francisco Giants will lock horns in MLB action at Citizens Bank Park on Tuesday, starting at 6:45PM ET.

The Phillies will send Jesús Luzardo (2-0, 1.50 ERA) to the mound, pitting him against Justin Verlander (0-0, 6.92 ERA) for the Giants.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Phillies as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's San Francisco-Philadelphia game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Phillies with a win probability of 58%, compared to 42% for the Giants."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Giants vs. Phillies predictions page.

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Giants vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Tuesday's MLB matchup between the Giants and Phillies 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Phillies a 58% chance of defeating the Giants.

According to our model, the Giants (+1.5) have a 60% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.

Pre-Game Probabilities

Last Updated: 10:28PM, Apr 15

Moneyline

Over / Under

Run Line

Giants

Win %

42%

58%

+140

-157

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See Matchup

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Phillies

Giants SF

+140

Win %

42%

58%

See Matchup

Phillies PHI

-157

Justin Verlander 0-0, 6.92 ERA

Jesús Luzardo 2-0, 1.50 ERA

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Giants vs. Phillies Odds [4/15/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Giants vs. Phillies Picks and Best Bets

Our model's strongest edge in today's Giants vs. Phillies matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Giants vs. Phillies Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Phillies and Giants at Citizens Bank Park is scheduled to start at 6:45PM ET.

• Who: San Francisco Giants vs. Philadelphia Phillies
• Date: Tuesday, April 15, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Citizens Bank Park

Dimers.com's full preview of Tuesday's Giants vs. Phillies matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Philadelphia picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Phillies, with a 58% win probability, will likely beat the Giants on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Phillies insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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