Giants vs. Yankees Prediction: Yankees Predicted to Win Saturday's MLB Matchup [4/12/2025]

MLB action continues on Saturday at 3:05PM ET as the San Francisco Giants take on the New York Yankees at Yankee Stadium.

Will Warren (0-0, 6.00 ERA) will get the ball for the Yankees, while the Giants will counter with Jordan Hicks (1-0, 2.38 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Yankees as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's San Francisco-NY Yankees game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Yankees are more likely to win, while the Giants have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Giants vs. Yankees predictions page.

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Giants vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's MLB game between the Giants and Yankees 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Yankees a 56% chance of defeating the Giants.

According to our model, the Giants (+1.5) have a 62% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.

Pre-Game Probabilities

Last Updated: 7:28PM, Apr 12

Moneyline

Over / Under

Run Line

Giants

Win %

43%

57%

+123

-135

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Yankees

Giants SF

+123

Win %

43%

57%

See Matchup

Yankees NYY

-135

Jordan Hicks 1-0, 2.38 ERA

Will Warren 0-0, 6.00 ERA

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Giants vs. Yankees Odds [4/12/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Giants vs. Yankees Picks and Best Bets

Our model's biggest edge in today's Giants vs. Yankees matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Giants vs. Yankees Game-Day Updates and Essential Details

Saturday's MLB game between the Yankees and Giants at Yankee Stadium is scheduled to start at 3:05PM ET.

• Who: San Francisco Giants vs. New York Yankees
• Date: Saturday, April 12, 2025
• Time: 3:05PM ET/12:05PM PT
• Venue: Yankee Stadium

Dimers.com's comprehensive preview of Saturday's Giants vs. Yankees matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. NY Yankees picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Yankees, with a 56% win probability, will likely beat the Giants on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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