49ers vs. Buccaneers Prediction: San Francisco Predicted to Win in NFL Week 10 [2024]

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Written by Mac Douglass
San Francisco 49ers-Tampa Bay Buccaneers Predictions and Game Preview.
Raymond James Stadium sets the stage for the NFL matchup between the San Francisco 49ers and Tampa Bay Buccaneers this Sunday.

NFL Week 10 action continues on Sunday at 1:00PM ET as the San Francisco 49ers take on the Tampa Bay Buccaneers at Raymond James Stadium.

Based on the latest simulations, Dimers' proven NFL model (see Dimers Pro for full access) predicts the 49ers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's 49ers-Buccaneers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 68%, while the Buccaneers have 32%."

This updated 49ers vs. Buccaneers betting preview is a follow-up on our early 49ers vs. Buccaneers prediction that was published at the start of the week.

For more detail on today’s game, including the predicted score, best bets and player prop picks, check out our interactive 49ers vs. Buccaneers predictions page.

49ers vs. Bucs Game-Day Updates and Essential Details

The NFL Week 10 game between the Buccaneers and 49ers at Raymond James Stadium is scheduled to commence at 1:00PM ET.

Dimers.com's full preview of Sunday's 49ers vs. Buccaneers matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Tampa Bay picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

READER EXCLUSIVE: Use code 20FOOTBALL at checkout now to get 20% off your first month of Dimers Pro! Hurry, this offer won't last long.

49ers vs. Buccaneers Predictions

Using trusted machine learning and data analysis, we have simulated the outcome of Sunday's NFL matchup between the 49ers and Buccaneers 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the 49ers a 68% chance of beating the Buccaneers in Week 10 of the NFL season. Our predicted final score has the 49ers winning 27-22.

According to our model, the Buccaneers (+6.5) have a 57% chance of covering the spread, while the over/under total of 50.5 points has an equal 50-50 chance of hitting.

 

Along with our 49ers vs. Buccaneers predictions, we've also got the following locked and loaded for today’s action:

49ers vs. Buccaneers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type 49ers Buccaneers
Spread -6.5 (-110) +6.5 (-102)
Moneyline -298 +250
Total o50.5 (-106) u50.5 (-112)

All odds are correct at the time of publication and are subject to change.

49ers vs. Buccaneers Picks

Our model's strongest edge in today's 49ers vs. Buccaneers matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

49ers vs. Buccaneers TD Scorers

Who will score the first touchdown in 49ers vs. Buccaneers?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first touchdown in 49ers vs. Buccaneers.

Our projections give McCaffrey a 15.5% chance of scoring the first TD at Raymond James Stadium, while the 49ers RB is a 61.8% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player First TD Probability
Christian McCaffrey 15.5%
Deebo Samuel 9.4%
George Kittle 9.0%

Tampa Bay Buccaneers

Player First TD Probability
Bucky Irving 7.7%
Cade Otton 7.6%
Rachaad White 7.3%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player Anytime TD Probability
Christian McCaffrey 61.8%
Deebo Samuel 42.7%
George Kittle 41.0%

Tampa Bay Buccaneers

Player Anytime TD Probability
Bucky Irving 36.9%
Cade Otton 36.5%
Rachaad White 34.4%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 10 touchdown scorer predictions

49ers vs Buccaneers Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the 49ers and Buccaneers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our 49ers-Buccaneers page now to access every player prop projection.

49ers vs. Buccaneers Quarterbacks

Of the starting quarterbacks, the 49ers' Brock Purdy is projected to throw for more yards than the Buccaneers' Baker Mayfield.

49ers Rushing

Christian McCaffrey, Jordan Mason and Deebo Samuel are projected to be the leading rushers for the 49ers.

Player Position
Christian McCaffrey RB
Jordan Mason RB
Deebo Samuel WR

Buccaneers Rushing

Bucky Irving, Rachaad White and Sean Tucker are expected to lead the Buccaneers in rushing yards.

Player Position
Bucky Irving RB
Rachaad White RB
Sean Tucker RB

49ers Receiving

George Kittle, Deebo Samuel, Jauan Jennings, Ricky Pearsall and Christian McCaffrey are projected to top the receiving yards for the 49ers.

Player Position
George Kittle TE
Deebo Samuel WR
Jauan Jennings WR
Ricky Pearsall WR
Christian McCaffrey RB

Buccaneers Receiving

Cade Otton, Jalen McMillan, Sterling Shepard, Trey Palmer and Rachaad White are projected to lead the Buccaneers in receiving yards.

Player Position
Cade Otton TE
Jalen McMillan WR
Sterling Shepard WR
Trey Palmer WR
Rachaad White RB

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Conclusion

We predict the 49ers, with a 68% win probability, will likely beat the Buccaneers on Sunday.

AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Buccaneers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on NFL

Stay up-to-date with the latest NFL betting news, NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date predictions for the Super Bowl, AFC, NFC and each division.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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