49ers vs. Seahawks Prediction: San Francisco Predicted to Win TNF Week 6 [2024]

The Seattle Seahawks and San Francisco 49ers will lock horns in Week 6 of the NFL season at Lumen Field on Thursday, with kickoff at 8:15PM ET.

Based on the latest simulations, Dimers' advanced NFL model (see Dimers Pro for full access) predicts the 49ers as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's 49ers-Seahawks game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the 49ers with a win probability of 60% and the Seahawks with 40%."

49ers vs. Seahawks Game-Day Updates and Essential Details

The NFL Week 6 action between the Seahawks and 49ers at Lumen Field is scheduled to begin at 8:15PM ET.

• Who: San Francisco 49ers vs. Seattle Seahawks
• Date: Thursday, October 10, 2024
• Time: 8:15PM ET/5:15PM PT
• Venue: Lumen Field
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Seahawks and 49ers gear at Fanatics

Dimers.com's full preview of Thursday's 49ers vs. Seahawks matchup includes our prediction, picks and the latest betting odds.

Before making any Seahawks vs. 49ers picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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49ers vs. Seahawks Predictions

Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's NFL matchup between the 49ers and Seahawks 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the 49ers a 60% chance of beating the Seahawks in Week 6 of the NFL season. Our predicted final score has the 49ers winning 25-22.

According to our model, the Seahawks (+3.5) have a 59% chance of covering the spread, while the 48.5-point over/under has a 51% chance of going over.

Along with our 49ers vs. Seahawks predictions, we've also here's what else we've got for this week's action:

• The Best NFL Week 6 Odds
• NFL Picks Straight Up for Week 6
• Picks Against The Spread for NFL Week 6

49ers vs. Seahawks Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	49ers	Seahawks
Spread	-3.5 (-110)	+3.5 (-102)
Moneyline	-190	+172
Total	o48.5 (-110)	u48.5 (-110)

All odds are correct at the time of publication and are subject to change.

49ers vs. Seahawks Picks

Our model's strongest edge in today's 49ers vs. Seahawks matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

49ers vs. Seahawks TD Scorers

Who will score the first touchdown in 49ers vs. Seahawks?

According to our model, San Francisco's Jordan Mason is most likely to score the first TD in 49ers vs. Seahawks.

Our projections give Mason a 15.1% chance of scoring the first TD at Lumen Field, while the 49ers RB is a 59.5% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player	First TD Probability
Jordan Mason	15.1%
Deebo Samuel	10.7%
George Kittle	8.2%

Seattle Seahawks

Player	First TD Probability
Kenneth Walker	10.0%
DK Metcalf	9.0%
Jaxon Smith-Njigba	7.2%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player	Anytime TD Probability
Jordan Mason	59.5%
Deebo Samuel	46.4%
Brandon Aiyuk	37.2%

Seattle Seahawks

Player	Anytime TD Probability
Kenneth Walker	44.9%
DK Metcalf	40.2%
Jaxon Smith-Njigba	33.8%

49ers vs Seahawks Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the 49ers and Seahawks. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our 49ers-Seahawks page now to access every player prop projection.

49ers vs. Seahawks Quarterbacks

Of the starting quarterbacks, the 49ers' Brock Purdy is projected to throw for more yards than the Seahawks' Geno Smith.

49ers Rushing

Jordan Mason, Brock Purdy and Deebo Samuel are projected to be the leading rushers for the 49ers.

Player	Position
Jordan Mason	RB
Brock Purdy	QB
Deebo Samuel	WR

Seahawks Rushing

Kenneth Walker, Zach Charbonnet and Geno Smith are expected to lead the Seahawks in rushing yards.

Player	Position
Kenneth Walker	RB
Zach Charbonnet	RB
Geno Smith	QB

49ers Receiving

Brandon Aiyuk, Deebo Samuel, George Kittle, Jauan Jennings and Jordan Mason are projected to top the receiving yards for the 49ers.

Player	Position
Brandon Aiyuk	WR
Deebo Samuel	WR
George Kittle	TE
Jauan Jennings	WR
Jordan Mason	RB

Seahawks Receiving

DK Metcalf, Jaxon Smith-Njigba, Tyler Lockett, Noah Fant and Kenneth Walker are projected to lead the Seahawks in receiving yards.

Player	Position
DK Metcalf	WR
Jaxon Smith-Njigba	WR
Tyler Lockett	WR
Noah Fant	TE
Kenneth Walker	RB

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Conclusion

We predict the 49ers, with a 60% win probability, will likely beat the Seahawks in Week 6 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Seahawks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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