49ers vs. Rams Prediction: San Francisco Predicted to Win Following Latest Data Analysis for NFL Week 3 [2024]

The Los Angeles Rams and San Francisco 49ers will lock horns in Week 3 of the NFL season at SoFi Stadium on Sunday, starting at 4:25PM ET.

Based on updated simulations, Dimers' advanced NFL model (see Dimers Pro for full access) projects the 49ers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's 49ers-Rams game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 69%, while the Rams have 31%."

49ers vs. Rams Game-Day Updates and Essential Details

The NFL Week 3 action between the Rams and 49ers at SoFi Stadium is scheduled to begin at 4:25PM ET.

• Who: San Francisco 49ers vs. Los Angeles Rams
• Date: Sunday, September 22, 2024
• Time: 4:25PM ET/1:25PM PT
• Venue: SoFi Stadium
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Rams and 49ers gear at Fanatics
• Live Stream: Watch this game on FOX via Hulu or FuboTV

Dimers.com's in-depth preview of this week's 49ers vs. Rams matchup includes our prediction, picks and the latest betting odds.

Before making any Rams vs. 49ers picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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49ers vs. Rams Predictions

Using trusted machine learning and data, we have simulated the outcome of Sunday's NFL game between the 49ers and Rams 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the 49ers a 69% chance of beating the Rams in Week 3 of the NFL season. Our predicted final score has the 49ers winning 25-19.

According to our model, the Rams (+6.5) have a 55% chance of covering the spread, while the 44.5-point over/under has an equal 50-50 chance of hitting.

As well as the above 49ers vs. Rams predictions, we also have the following locked and loaded for today's action:

• NFL Best Bets for Week 3
• NFL Player Props for Week 3
• Touchdown Predictions for Week 3

49ers vs. Rams Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	49ers	Rams
Spread	-6.5 (-102)	+6.5 (-120)
Moneyline	-258	+230
Total	o44.5 (-110)	u44.5 (-106)

All odds are correct at the time of publication and are subject to change.

49ers vs. Rams Picks

Our model's biggest edge in today's 49ers vs. Rams matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best NFL picks for every game throughout the season.

Full access to our picks, including this one, is available via Dimers Pro.

49ers vs. Rams TD Scorers

Who will score the first touchdown in 49ers vs. Rams?

According to our model, San Francisco's Jordan Mason is most likely to score the first TD in 49ers vs. Rams.

Our projections give Mason a 17.6% chance of scoring the first TD at SoFi Stadium, while the 49ers RB is a 62.2% chance of registering an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player	First TD Probability
Jordan Mason	17.6%
Brandon Aiyuk	11.7%
Jauan Jennings	6.8%

Los Angeles Rams

Player	First TD Probability
Kyren Williams	12.2%
Demarcus Robinson	7.7%
Jordan Whittington	5.5%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player	Anytime TD Probability
Jordan Mason	62.2%
Brandon Aiyuk	45.6%
Jauan Jennings	31.2%

Los Angeles Rams

Player	Anytime TD Probability
Kyren Williams	48.9%
Demarcus Robinson	32.7%
Jordan Whittington	24.2%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 3 touchdown scorer predictions

49ers vs Rams Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the 49ers and Rams. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our 49ers-Rams page now to access every player prop projection.

49ers vs. Rams Quarterbacks

Of the starting quarterbacks, the 49ers' Brock Purdy is projected to throw for more yards than the Rams' Matthew Stafford.

49ers Rushing

Jordan Mason, Brock Purdy and Isaac Guerendo are projected to be the leading rushers for the 49ers.

Player	Position
Jordan Mason	RB
Brock Purdy	QB
Isaac Guerendo	RB

Rams Rushing

Kyren Williams, Blake Corum and Ronnie Rivers are expected to lead the Rams in rushing yards.

Player	Position
Kyren Williams	RB
Blake Corum	RB
Ronnie Rivers	RB

49ers Receiving

Brandon Aiyuk, Jauan Jennings, Eric Saubert, Chris Conley and Jacob Cowing are projected to top the receiving yards for the 49ers.

Player	Position
Brandon Aiyuk	WR
Jauan Jennings	WR
Eric Saubert	TE
Chris Conley	WR
Jacob Cowing	WR

Rams Receiving

Demarcus Robinson, Tyler Johnson, Colby Parkinson, Jordan Whittington and Tutu Atwell are projected to lead the Rams in receiving yards.

Player	Position
Demarcus Robinson	WR
Tyler Johnson	WR
Colby Parkinson	TE
Jordan Whittington	WR
Tutu Atwell	WR

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Conclusion

We predict the 49ers, with a 69% win probability, will likely beat the Rams in Week 3 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Rams insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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