49ers vs. Packers Prediction: Green Bay Predicted to Win in NFL Week 12 [2024]

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Written by Jason Bevilacqua

Our expert prediction for Sunday's San Francisco 49ers vs Green Bay Packers matchup.

San Francisco 49ers-Green Bay Packers Predictions and Game Preview.
Lambeau Field sets the stage for the NFL matchup between the San Francisco 49ers and Green Bay Packers this Sunday.

The Green Bay Packers will take on the San Francisco 49ers in NFL Week 12 action at Lambeau Field on Sunday, starting at 4:25PM ET.

Based on updated simulations, Dimers' proven NFL model (see Dimers Pro for full access) predicts the Packers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's San Francisco-Green Bay game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Packers with a win probability of 73%, while the 49ers have 27%."

This updated 49ers vs. Packers betting preview builds on my early 49ers vs. Packers prediction that I released at the start of the week.

For a closer look at today’s game, including the predicted score, best bets and player prop picks, visit our interactive 49ers vs. Packers predictions page.

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49ers vs. Packers Game-Day Updates and Essential Details

The NFL Week 12 action between the Packers and 49ers at Lambeau Field is scheduled to commence at 4:25PM ET.

Dimers.com's comprehensive preview of Sunday's 49ers vs. Packers matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Green Bay picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

49ers vs. Packers Predictions

Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's NFL game between the 49ers and Packers 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Packers a 73% chance of beating the 49ers in Week 12 of the NFL season. Our predicted final score has the Packers winning 25-19.

According to our model, the bookies have got it right, and the 49ers and Packers each have a 50% chance of covering the spread, while the 44.5-point over/under has a 55% chance of going over.

 

Along with our 49ers vs. Packers predictions, we've also here's what else we've got for today’s action:

49ers vs. Packers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type 49ers Packers
Spread +6.5 (-112) -6.5 (-105)
Moneyline +240 -290
Total o44.5 (-112) u44.5 (-104)

All odds are correct at the time of publication and are subject to change.

49ers vs. Packers Picks

Our model's strongest edge in today's 49ers vs. Packers matchup is on the spread.

Our expert predictions, matched against the best odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

49ers vs. Packers TD Scorers

Who will score an anytime touchdown in 49ers vs. Packers?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first touchdown in 49ers vs. Packers.

Our projections give McCaffrey a 13.0% chance of scoring the first TD at Lambeau Field, while the 49ers RB is a 52.1% chance of registering an anytime touchdown.

First Touchdown Scorer Predictions

San Francisco 49ers

Player First TD Probability
Christian McCaffrey 13.0%
Deebo Samuel 7.1%
George Kittle 7.0%

Green Bay Packers

Player First TD Probability
Josh Jacobs 12.8%
Jayden Reed 8.9%
Christian Watson 6.6%

Anytime Touchdown Scorer Predictions

San Francisco 49ers

Player Anytime TD Probability
Christian McCaffrey 52.1%
George Kittle 31.9%
Deebo Samuel 31.6%

Green Bay Packers

Player Anytime TD Probability
Josh Jacobs 49.5%
Jayden Reed 37.8%
Christian Watson 29.9%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 12 touchdown scorer predictions

49ers vs Packers Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the 49ers and Packers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our 49ers-Packers page now to access every player prop projection.

49ers vs. Packers Quarterbacks

Of the starting quarterbacks, the 49ers' Brandon Allen is projected to throw for fewer yards than the Packers' Jordan Love.

49ers Rushing

Christian McCaffrey, Jordan Mason and Deebo Samuel are projected to be the leading rushers for the 49ers.

Player Position
Christian McCaffrey RB
Jordan Mason RB
Deebo Samuel WR

Packers Rushing

Josh Jacobs, Emanuel Wilson and Jordan Love are expected to lead the Packers in rushing yards.

Player Position
Josh Jacobs RB
Emanuel Wilson RB
Jordan Love QB

49ers Receiving

George Kittle, Jauan Jennings, Deebo Samuel, Ricky Pearsall and Christian McCaffrey are projected to top the receiving yards for the 49ers.

Player Position
George Kittle TE
Jauan Jennings WR
Deebo Samuel WR
Ricky Pearsall WR
Christian McCaffrey RB

Packers Receiving

Jayden Reed, Romeo Doubs, Christian Watson, Tucker Kraft and Dontayvion Wicks are projected to lead the Packers in receiving yards.

Player Position
Jayden Reed WR
Romeo Doubs WR
Christian Watson WR
Tucker Kraft TE
Dontayvion Wicks WR

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Conclusion

We predict the Packers, with a 73% win probability, will likely beat the 49ers in Week 12 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Packers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NFL

Stay informed with the latest NFL betting news, NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds offer the most accurate projections for the Super Bowl, AFC, NFC and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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