San Francisco 49ers vs. Buffalo Bills Early Prediction for NFL Week 13 [2024]

The Buffalo Bills and San Francisco 49ers will face off against each other in Week 13 of the NFL season at Highmark Stadium on Sunday, December 1, 2024, with kickoff at 8:20PM ET.

Based on early simulation results, Dimers' proven NFL model (see Dimers Pro for full access) predicts the 49ers as the most likely winner of this Week 13 game.

49ers vs. Bills Essential Details

The NFL Week 13 matchup between the Bills and 49ers at Highmark Stadium is scheduled for December.

• Who: San Francisco 49ers vs. Buffalo Bills
• Date: Sunday, December 1, 2024
• Time: 8:20PM ET/5:20PM PT
• Venue: Highmark Stadium
• Tickets: Get tickets for the game on Ticketmaster

Before making any 49ers vs. Bills picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

San Francisco vs. Buffalo Early Prediction: Model Forecasts 49ers to Win

Using powerful machine learning and analysis, we have simulated the outcome of the NFL Week 13 game between the 49ers and Bills 10,000 times as part of our NFL picks coverage.

Our famous predictive model gives the 49ers a 58% chance of beating the Bills in Week 13 of the NFL season. Our predicted final score has the 49ers winning 24-22.

According to our model, the bookmakers have got it right, and the 49ers and Bills each have a 50% chance of covering the spread, while the 47-point over/under has a 51% chance of staying under.

As of July 2024, these 49ers-Bills predictions reflect the most up-to-date data and insights available.

Conclusion

We predict the 49ers, with a 58% win probability, will likely beat the Bills in Week 13 of the NFL season.

Dimers.com will have full coverage of the game closer to kickoff, so stay tuned for more updates.

AI and automation have enhanced this article to quickly deliver accurate 49ers vs. Bills insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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