Reds vs. Pirates Prediction and Odds - Sep 27, 2022

The Pittsburgh Pirates take on the Cincinnati Reds in MLB action at PNC Park on Tuesday, commencing at 6:35PM ET.

The Pirates will send Mitch Keller (5-12, 3.99 ERA) to the mound, pitting him against Hunter Greene (4-13, 4.91 ERA) for the Reds.

Dimers' top betting picks for Reds vs. Pirates, as well as game predictions and best odds, are detailed below.

Who will win Reds vs. Pirates?

Using advanced machine learning and data, Dimers.com has simulated Tuesday's Reds-Pirates MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Pirates a 51% chance of getting the W against the Reds.

More: Full Betting Guide for Reds vs. Pirates

Reds vs. Pirates Current Odds

• Run Line: Pirates +1.5 (-194), Reds -1.5 (+170)
• Moneyline: Pirates -115, Reds -102
• Total: Over/Under 7 (-105/-110)

Run Line, Moneyline and Over/Under

The Pirates are +1.5 underdogs against the Reds, with -194 at FanDuel Sportsbook the best odds currently available.

For the favored Reds (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +170.

In a sign of how close this game is expected to be, both the Pirates and Reds are currently at minus-money betting odds on the moneyline.

Caesars Sportsbook currently has the best moneyline odds for the Pirates at -115. That means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Reds at -102, where you can risk $102 to win $100, for a total payout of $202, if they come out on top.

The Over/Under for total runs scored sits at 7 with FanDuel Sportsbook, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, make sure you check all of the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 63% chance of covering the run line, while the 7-run Over/Under is a 52% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Reds vs. Pirates

• Run Line: Reds -1.5 @ +170 via DraftKings Sportsbook
• Moneyline: Reds @ -102 via FanDuel Sportsbook
• Total: Over 7 @ -105 via FanDuel Sportsbook (52% probability)

Dimers' best bets are based on world-class modeling and wagering expertise to help you make smarter decisions with your state's legal sportsbooks.

Even though the Pirates are more likely to cover the run line, our best bet of Reds -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

And while the Pirates are more likely to win the game, according to DimersBOT, taking the Reds moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is pivotal to being profitable in the long run.

Reds vs. Pirates Prediction

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Dimers has full coverage of Tuesday's Reds-Pirates matchup, including pregame predictions, best betting picks, and live scores.

Don't forget, DimersBOT updates often, so refresh this page for any changes to our betting analysis ahead of Reds vs. Pirates on Tuesday September 27, 2022.

Reds vs. Pirates 2022 Game Info

Tuesday's action between the Pirates and Reds at PNC Park is scheduled to begin at 6:35PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Tuesday September 27, 2022
• Time: 6:35PM ET / 3:35PM PT
• Venue: PNC Park

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