Reds vs. Pirates Prediction and Odds - Aug 21, 2022

The Pittsburgh Pirates and Cincinnati Reds clash in MLB at PNC Park on Sunday, starting at 1:35PM ET.

Zach Thompson (3-9, 5.51 ERA) will start for the Pirates, pitting him against Mike Minor (1-10, 6.31 ERA) for the Reds.

Dimers' top betting picks for Reds vs. Pirates, as well as game predictions and betting odds, are detailed below.

Who will win Reds vs. Pirates?

Based on cutting-edge computer power and data, Dimers.com has simulated Sunday's Reds-Pirates MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Pirates a 53% chance of beating the Reds.

More: Reds vs. Pirates Simulated 10,000 Times

Reds vs. Pirates Game Odds

• Run Line: Pirates +1.5 (-190), Reds -1.5 (+158)
• Moneyline: Pirates -120, Reds +102
• Total: Over/Under 8.5 (-118/+105)

Run Line, Moneyline and Over/Under

The Pirates are +1.5 underdogs versus the Reds, with -190 at BetMGM the best odds currently available.

For the favored Reds (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +158.

BetMGM currently has the best moneyline odds for the Pirates at -120, which means you can risk $120 to win $100, for a total payout of $220, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Reds at +102, where you can bet $100 to profit $102, earning a total payout of $202, if they win.

The Over/Under sits at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, while PointsBet currently has the best odds for the Under at +105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 66% chance of covering the run line, while the Over/Under total of 8.5 runs is a 51% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Reds vs. Pirates

• Run Line: Pirates +1.5 @ -190 via BetMGM (66% probability)
• Moneyline: Pirates @ -120 via BetMGM (53% probability)
• Total: Under 8.5 @ +105 via PointsBet

Our best bets are based on complex simulations and wagering intelligence to help you make smarter investments with the legal sportsbooks in the USA.

Despite the Over being more likely to hit on this occasion, Under 8.5 is our best bet owing to the better odds (+105) that are available from PointsBet.

Reds vs. Pirates Prediction

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Cincinnati vs. Pittsburgh, and click or tap on See Matchup for more.

Dimers has full betting coverage of Sunday's Reds-Pirates matchup, including pregame predictions, free picks, and live scores.

Remember, DimersBOT updates frequently, so keep an eye on this page for the latest betting insights before Reds vs. Pirates on Sunday August 21, 2022.

Risk-Free Bet for Reds vs. Pirates

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All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Reds vs. Pirates 2022 Game Info

Sunday's action between the Pirates and Reds at PNC Park is scheduled to begin at 1:35PM ET.

• Who: Pittsburgh Pirates vs. Cincinnati Reds
• Date: Sunday August 21, 2022
• Time: 1:35PM ET / 10:35AM PT
• Venue: PNC Park

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Want more MLB predictions like this?

To get more MLB betting previews like you've just read for Reds vs. Pirates, all you've gotta do is visit our MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the most comprehensive MLB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds on the market.