Reds vs. Pirates Prediction and Odds - Apr 21, 2023

MLB action continues on Friday at 6:35PM ET as the Cincinnati Reds take on the Pittsburgh Pirates at PNC Park.

The Pirates will have Mitch Keller (1-0, 3.80 ERA) start, while the Reds are going with Graham Ashcraft (2-0, 1.42 ERA).

Dimers' top betting picks for Reds vs. Pirates, as well as game predictions and best odds, are featured below.

Who will win Reds vs. Pirates?

Using advanced computer power and data, Dimers.com has simulated Friday's Reds-Pirates MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Pirates a 57% chance of winning against the Reds.

More: Free Betting Guide for Reds vs. Pirates

Reds vs. Pirates Odds

• Run Line: Pirates -1.5 (+140), Reds +1.5 (-162)
• Moneyline: Pirates -145, Reds +130
• Total: Over/Under 8.5 (-115/-104)

Run Line, Moneyline and Over/Under

The Pirates are currently -1.5 favorites against the Reds, with +140 at BetMGM the best odds currently available.

For the underdog Reds (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -162.

PointsBet currently has the best moneyline odds for the Pirates at -145. That means you can risk $145 to win $100, for a total payout of $245, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Reds at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under for total runs scored is set at 8.5 with PointsBet, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 61% chance of covering the run line, while the 8.5-run Over/Under is a 53% chance of going Under.

More: Free Online Bet Tracking Tool

Best Bets for Reds vs. Pirates

• Run Line: Reds +1.5 @ -162 via FanDuel Sportsbook (61% probability)
• Moneyline: Reds @ +130 via DraftKings Sportsbook
• Total: Under 8.5 @ -104 via FanDuel Sportsbook (53% probability)

Our best bets are based on world-class simulations and betting intelligence to help you make more informed investments with your state's legal sportsbooks.

While the Pirates are more likely to win the game, according to DimersBOT, betting on the Reds moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is pivotal to achieving long-term profitability as a sports bettor.

Reds vs. Pirates Prediction

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Dimers has full betting coverage of Friday's Reds-Pirates matchup, including pregame predictions, free betting picks, and live updates.

Remember, DimersBOT updates often, so keep checking this page for any changes to our betting analysis ahead of Reds vs. Pirates on Friday April 21, 2023.

Reds vs. Pirates 2023 Game Info

Friday's game between the Pirates and Reds at PNC Park is scheduled to start at 6:35PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Friday April 21, 2023
• Time: 6:35PM ET / 3:35PM PT
• Venue: PNC Park

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So, you liked our Reds vs. Pirates betting predictions? Awesome. Did you know our MLB Betting News page has a detailed betting preview for every MLB matchup as soon as the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets. This allows us to create the most reliable MLB betting previews and get the jump on the public and the sportsbooks.

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Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities compared to the best odds available.