Reds vs. Guardians Prediction and Odds - May 19, 2022

The Cleveland Guardians and Cincinnati Reds are scheduled to meet in MLB at Progressive Field on Thursday, starting at 1:10PM ET.

The Guardians will have Cal Quantrill (1-2, 3.93 ERA) start, while the Reds will counter with Tyler Mahle (2-4, 5.89 ERA).

Dimers' free betting picks for Reds vs. Guardians, plus game predictions and best odds, are detailed below.

Today's Cincinnati vs. Cleveland betting preview is brought to you by PointsBet, which has an awesome 5x $100 Risk-Free Bets promo for new customers.

Who will win Reds vs. Guardians?

Using trusted machine learning and data, Dimers.com has simulated Thursday's Reds-Guardians MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Guardians a 57% chance of defeating the Reds .

More: Reds vs. Guardians Simulated 10K Times

Reds vs. Guardians Current Odds

• Run Line: Guardians -1.5 (+165), Reds +1.5 (-110)
• Moneyline: Guardians -130, Reds +115
• Total: Over/Under 8.5 (-105/-115)

Run Line, Moneyline and Over/Under

The Guardians are -1.5 favorites against the Reds, with +165 at DraftKings Sportsbook the best odds currently available.

For the underdog Reds (+1.5) to cover the run line, PointsBet has the best odds currently on offer at -110.

Caesars Sportsbook currently has the best moneyline odds for the Guardians at -130. That means you can risk $130 to win $100, for a total payout of $230, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Reds at +115, where you can bet $100 to profit $115, earning a total payout of $215, if they win.

The Over/Under is set at 8.5 with PointsBet, which currently has the best odds for the Over at -105, as well as the best odds for the Under at -115.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 8.5 runs is a 54% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets for Reds vs. Guardians

• Run Line: Reds +1.5 @ -110 via PointsBet (61% probability) 🔥
• Moneyline: Guardians @ -130 via Caesars Sportsbook (57% probability)
• Total: Under 8.5 @ -115 via PointsBet (54% probability)

Every time you see a 🔥, that means you've found one of Dimers' best bets of the day across any sport.

Dimers' best bets are based on world-class simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in your state.

Reds vs. Guardians Probabilities

Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cincinnati vs. Cleveland, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Thursday's Reds-Guardians matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting analysis ahead of Reds vs. Guardians on Thursday May 19, 2022.

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Reds vs. Guardians 2022 Game Info

Thursday's game between the Guardians and Reds at Progressive Field is scheduled to begin at 1:10PM ET.

• Date: Thursday May 19, 2022
• Time: 1:10PM ET / 10:10AM PT
• Venue: Progressive Field

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What MLB games are on today?

The Reds and Guardians aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every MLB game in our MLB Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.