Rams vs. Cardinals Predictions and Odds - Dec 13, 2021

The Arizona Cardinals square off with the Los Angeles Rams in NFL Week 14 action at State Farm Stadium on Monday, starting at 8:15 PM EST.

Dimers' top betting picks for Rams vs. Cardinals, plus our score prediction, best odds and player props, are detailed below.

Who will win Rams vs. Cardinals?

Based on advanced machine learning and data, Dimers.com has simulated Monday's Rams-Cardinals NFL game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Cardinals a 59% chance of beating the Rams.

MORE: Rams vs. Cardinals Simulated 10K Times

Point Spread, Moneyline and Over/Under

The Cardinals are -3 favorites against the Rams, with -110 at BetMGM the best odds available.

For the underdog Rams (+3) to cover the spread, BetMGM also has the best odds on offer at -110.

FanDuel Sportsbook has the best moneyline odds for the Cardinals at -158. That means you can risk $158 to win $100, for a total payout of $258, if they get the W.

Meanwhile, DraftKings Sportsbook has the best moneyline odds for the Rams at +140, where you can bet $100 to profit $140, earning a total payout of $240, if they win.

The Over/Under for total points scored sits at 51.5 with FanDuel Sportsbook, which has the best odds for the Over at -105, as well as the best odds for the Under at -115.

As always, check out all the sportsbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Rams and Cardinals are a 50% chance of covering the spread, while the 51.5-point Over/Under is a 56% chance of going Under.

MORE: Predictions for Every NFL Week 14 Game

Best Bets for Rams vs. Cardinals

• Spread: Rams +3 at -110 with BetMGM (50% probability)
• Moneyline: Rams Win at +140 with DraftKings Sportsbook
• Over/Under: Under 51.5 at -115 with FanDuel Sportsbook (56% probability)

While the Cardinals are more likely to win the game, according to DimersBOT, betting on the Rams moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges published here at Dimers is one of the keys to being profitable in the long run.

Rams vs. Cardinals Score Prediction

Dimers.com's predicted final score for LA Rams vs. Arizona at State Farm Stadium this Monday has the Cardinals winning 26-23.

Use our dynamic widget below to see the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Rams-Cardinals matchup, including pre-game predictions, free betting picks, and live win probabilities.

Rams vs. Cardinals Player Props

Who will score an anytime touchdown in Rams vs. Cardinals? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Rams and Cardinals, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you discover the best prop picks for Monday's game.

According to DimersBOT, Arizona's James Conner is most likely to score the first TD in Rams vs. Cardinals.

DimersBOT gives Conner a 17.2% chance of scoring the first TD at State Farm Stadium, while the Cardinals RB is a 64.6% chance of scoring an anytime touchdown.

First Touchdown Scorer Probabilities

Los Angeles Rams

• Cooper Kupp: 14.5% probability
• Sony Michel: 9.5% probability
• Odell Beckham: 8.0% probability
• Van Jefferson: 5.5% probability
• Ben Skowronek: 2.8% probability

Arizona Cardinals

• James Conner: 17.2% probability
• Kyler Murray: 8.1% probability
• DeAndre Hopkins: 7.4% probability
• Christian Kirk: 4.7% probability
• Zach Ertz: 4.1% probability

Anytime Touchdown Scorer Probabilities

Los Angeles Rams

• Cooper Kupp: 57.1% probability
• Sony Michel: 43.6% probability
• Odell Beckham: 38.2% probability
• Van Jefferson: 28.9% probability
• Ben Skowronek: 15.8% probability

Arizona Cardinals

• James Conner: 64.6% probability
• Kyler Murray: 38.4% probability
• DeAndre Hopkins: 34.5% probability
• Christian Kirk: 25.6% probability
• A.J. Green: 22.4% probability

Projected Box Score

Of the starting quarterbacks, the Rams' Matthew Stafford is projected to have a big game with 298 passing yards and 2.0 passing touchdowns. The Cardinals' Kyler Murray is expected to throw for 253 yards and 1.7 TDs.

Rams Starting QB

• Matthew Stafford: 298 Passing Yards, 2.0 Passing TDs

Cardinals Starting QB

• Kyler Murray: 253 Passing Yards, 1.7 Passing TDs

Rams Rushing

• Sony Michel: 79 Rushing Yards, 0.4 TDs
• Mekhi Sargent: 15 Rushing Yards, 0.1 TDs
• Matthew Stafford: 9 Rushing Yards, 0.1 TDs

Cardinals Rushing

• James Conner: 68 Rushing Yards, 0.9 TDs
• Kyler Murray: 36 Rushing Yards, 0.5 TDs
• Eno Benjamin: 12 Rushing Yards, 0.1 TDs

Rams Receiving

• Cooper Kupp: 112 Receiving Yards, 0.8 TDs
• Van Jefferson: 61 Receiving Yards, 0.3 TDs
• Odell Beckham: 51 Receiving Yards, 0.4 TDs
• Ben Skowronek: 20 Receiving Yards, 0.2 TDs
• Sony Michel: 18 Receiving Yards, 0.1 TDs

Cardinals Receiving

• DeAndre Hopkins: 73 Receiving Yards, 0.4 TDs
• Christian Kirk: 54 Receiving Yards, 0.3 TDs
• A.J. Green: 40 Receiving Yards, 0.2 TDs
• Rondale Moore: 33 Receiving Yards, 0.2 TDs
• Zach Ertz: 33 Receiving Yards, 0.2 TDs

Don't forget, DimersBOT updates regularly, so refresh this article for any changes to our betting analysis ahead of Rams vs. Cardinals on Monday December 13, 2021.

Rams vs. Cardinals 2021 Game Info

When do the Cardinals play the Rams?

• Date: Monday December 13, 2021
• Time: 8:15 PM EST / 5:15 PM PST
• Venue: State Farm Stadium

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