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Pumas UNAM vs. Santos Laguna Prediction, Odds, Liga MX Picks [4/16/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Our expert prediction for Wednesday's Pumas UNAM vs Santos Laguna matchup.
Pumas UNAM will face Santos Laguna in the Liga MX playoffs at Estadio Olímpico Universitario on Wednesday, beginning at 11:05PM ET.
Based on updated simulation results, Dimers' proven Liga MX model (see Dimers Pro for full access) predicts Pumas UNAM as the most likely winner of today's game.
"Our team has simulated the outcome of Wednesday's Pumas UNAM-Santos Laguna game 10,000 times," said Dave Garofolo from Dimers.
"Taking into account the most current updates and numerous additional factors, our prediction gives Pumas UNAM a 72.0% chance of winning, Santos Laguna a 10.3% chance, and a 17.7% chance of a draw."
For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Pumas UNAM vs. Santos Laguna predictions page.
Get 20% off Dimers Pro With Code 20SOCCER Get Dimers Pro Pumas UNAM vs. Santos Laguna Prediction: Who Will Win?
Using powerful machine learning and data, we have simulated the result of Wednesday's Liga MX game between Pumas UNAM and Santos Laguna 10,000 times as part of our Liga MX predictions coverage.
Our independent predictive model currently indicates a 72.0% chance of Pumas UNAM winning, a 10.3% chance for Santos Laguna, and a 17.7% chance of a draw.
Additionally, the over/under total of 2.5 goals has a 55% chance of going over, according to our model.
Pumas UNAM vs. Santos Laguna Odds
We have researched the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Pumas UNAM | Santos Laguna | Draw |
|---|---|---|
| -295 | +850 | +450 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -180 | +130 |
All odds are correct at the time of publication and are subject to change.
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Pumas UNAM vs. Santos Laguna Picks and Best Bets
Our model's biggest edge in today's Pumas UNAM vs. Santos Laguna matchup is on the total.
Our expert predictions, aligned with the best odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Unlock Every Pumas UNAM-Santos Laguna Pick Get Dimers Pro Pumas UNAM vs. Santos Laguna: Correct Score and BTTS Predictions
Here are the top three most likely final scores according to our model, with a 2-0 Pumas UNAM win being the most probable:
| Final Score | Probability |
|---|---|
| PUM 2-0 SLA | 13.4% |
| PUM 1-0 SLA | 12.1% |
| PUM 3-0 SLA | 9.8% |
When it comes to the both teams to score (BTTS) market, we project a 44.6% chance that both Pumas UNAM and Santos Laguna score, and a 55.4% probability of at least one team keeping a clean sheet.
These predictions are based on each team's average score after 10,000 simulations.
Pumas UNAM vs. Santos Laguna Game-Day Updates and Essential Details
Wednesday's game between Pumas UNAM and Santos Laguna at Estadio Olímpico Universitario is scheduled to commence at 11:05PM ET.
- Who: Pumas UNAM vs. Santos Laguna
- Date: Wednesday, April 16, 2025
- Time: 11:05PM ET/8:05PM PT
- Venue: Estadio Olímpico Universitario
Dimers.com's comprehensive preview of Wednesday's Pumas UNAM vs. Santos Laguna matchup includes our prediction, picks and the latest betting odds.
Before making any Santos Laguna vs. Pumas UNAM picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.
Conclusion
According to our computer model, Pumas UNAM has a 72.0% win probability on Wednesday, Santos Laguna has a 10.3% win probability, and there is a 17.7% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Pumas UNAM vs. Santos Laguna insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on Liga MX
Stay up-to-date with the latest Liga MX news and parlay picks throughout the season.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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